Role of interleukin-16 in human diseases: a novel potential therapeutic target

Interleukin (IL)-16 is expressed mostly by the cells of the human immune system. Upon cell activation IL-16 is cleaved, forming two functional proteins, one regulating cell cycle and the other acting as chemoattractant for the cells carrying CD4 or CD9. Increased levels of IL-16 are found in the cir...

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Bibliographic Details
Main Authors: Timothy B. Niewold, Julia S. Lehman, Iva Gunnarsson, Alexander Meves, Vilija Oke
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1524026/full
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