Insulin resistance as a potential driving force of parental obesity-induced adverse metabolic programming mechanisms in children with obesity

Insulin resistance as a potential driving force of parental obesity-induced adverse metabolic programming mechanisms in children with obesity

Abstract Background Parental obesity has been identified as one of the most important early risk factors for childhood obesity, but molecular mechanisms driving this greater predisposition remain to be elucidated. Methods In this study, we recruited a cohort comprising children with obesity (body ma...

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Bibliographic Details
Main Authors: Lucía Jurado-Sumariva, Álvaro González-Domínguez, Otto Savolainen, Jesús Domínguez-Riscart, Rikard Landberg, Raúl González-Domínguez
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Medicine
Subjects:
Childhood obesity
Insulin resistance
Metabolomics
Parental obesity
Online Access:https://doi.org/10.1186/s12916-025-04282-w
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