Understanding the effects of mild traumatic brain injury on the pupillary light reflex
The pupillary light reflex represents an optimal visual system to investigate and exploit in the mild traumatic brain injury (mTBI) population. Static and dynamic aspects of the pupillary light reflex were investigated objectively and quantitatively in the mTBI population. Pupillary responsivity was...
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| Format: | Article |
| Language: | English |
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Aldus Press
2017-11-01
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| Series: | Concussion |
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| Online Access: | https://www.futuremedicine.com/doi/10.2217/cnc-2016-0029 |
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| _version_ | 1849768571019722752 |
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| author | Kenneth J Ciuffreda Nabin R Joshi James Q Truong |
| author_facet | Kenneth J Ciuffreda Nabin R Joshi James Q Truong |
| author_sort | Kenneth J Ciuffreda |
| collection | DOAJ |
| description | The pupillary light reflex represents an optimal visual system to investigate and exploit in the mild traumatic brain injury (mTBI) population. Static and dynamic aspects of the pupillary light reflex were investigated objectively and quantitatively in the mTBI population. Pupillary responsivity was found to be significantly delayed, slowed and reduced, but symmetrical in nature, and with a smaller baseline diameter, as compared with normals. Several pupillary parameters also discriminated between those with versus without photosensitivity. Thus, dynamic pupillometry provides several objective biomarkers for the presence of mTBI and photosensitivity, gives insight into the global sites of neurological dysfunction and possible related mechanisms, and should result in improved patient care. |
| format | Article |
| id | doaj-art-1d3cb659749849b38c5f147d3f13019f |
| institution | DOAJ |
| issn | 2056-3299 |
| language | English |
| publishDate | 2017-11-01 |
| publisher | Aldus Press |
| record_format | Article |
| series | Concussion |
| spelling | doaj-art-1d3cb659749849b38c5f147d3f13019f2025-08-20T03:03:45ZengAldus PressConcussion2056-32992017-11-012310.2217/cnc-2016-0029Understanding the effects of mild traumatic brain injury on the pupillary light reflexKenneth J Ciuffreda0Nabin R Joshi1James Q Truong21Brain Injury Research Clinic, SUNY/State College of Optometry, 33 West 42nd Street, New York City, NY 10036, USA1Brain Injury Research Clinic, SUNY/State College of Optometry, 33 West 42nd Street, New York City, NY 10036, USA1Brain Injury Research Clinic, SUNY/State College of Optometry, 33 West 42nd Street, New York City, NY 10036, USAThe pupillary light reflex represents an optimal visual system to investigate and exploit in the mild traumatic brain injury (mTBI) population. Static and dynamic aspects of the pupillary light reflex were investigated objectively and quantitatively in the mTBI population. Pupillary responsivity was found to be significantly delayed, slowed and reduced, but symmetrical in nature, and with a smaller baseline diameter, as compared with normals. Several pupillary parameters also discriminated between those with versus without photosensitivity. Thus, dynamic pupillometry provides several objective biomarkers for the presence of mTBI and photosensitivity, gives insight into the global sites of neurological dysfunction and possible related mechanisms, and should result in improved patient care.https://www.futuremedicine.com/doi/10.2217/cnc-2016-0029mTBImild traumatic brain injuryphotosensitivityPLRpupillary light reflex |
| spellingShingle | Kenneth J Ciuffreda Nabin R Joshi James Q Truong Understanding the effects of mild traumatic brain injury on the pupillary light reflex Concussion mTBI mild traumatic brain injury photosensitivity PLR pupillary light reflex |
| title | Understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| title_full | Understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| title_fullStr | Understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| title_full_unstemmed | Understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| title_short | Understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| title_sort | understanding the effects of mild traumatic brain injury on the pupillary light reflex |
| topic | mTBI mild traumatic brain injury photosensitivity PLR pupillary light reflex |
| url | https://www.futuremedicine.com/doi/10.2217/cnc-2016-0029 |
| work_keys_str_mv | AT kennethjciuffreda understandingtheeffectsofmildtraumaticbraininjuryonthepupillarylightreflex AT nabinrjoshi understandingtheeffectsofmildtraumaticbraininjuryonthepupillarylightreflex AT jamesqtruong understandingtheeffectsofmildtraumaticbraininjuryonthepupillarylightreflex |