Photodynamic therapy for severe acne
Acne is an inflammatory cutaneous disease affecting the pilosebaceous unit and hair follicles on the face, neck, back, and chest, with a typical onset in adolescence and, in some cases, persisting into adulthood. Systemic treatments with antibiotics or isotretinoin present many limitations, like ant...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100023006208 |
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| author | Federica Li Pomi Mario Vaccaro Lucia Peterle Francesco Borgia |
| author_facet | Federica Li Pomi Mario Vaccaro Lucia Peterle Francesco Borgia |
| author_sort | Federica Li Pomi |
| collection | DOAJ |
| description | Acne is an inflammatory cutaneous disease affecting the pilosebaceous unit and hair follicles on the face, neck, back, and chest, with a typical onset in adolescence and, in some cases, persisting into adulthood. Systemic treatments with antibiotics or isotretinoin present many limitations, like antimicrobial resistance phenomena and teratogenicity, which appear more relevant in the pediatric population, both for the treatment-related risks and for the reticence of the parents. Photodynamic therapy (PDT) has already shown encouraging results in the treatment of acne in adult patients, with good aesthetic results compared to other therapies and few side effects. However, its use is still not standardized in the pediatric population. On this topic, we report our experience with PDT in a young patient affected by dorsal acne. After five sessions of ALA-PDT at monthly intervals, a remarkable improvement of the lesions was observed, with the healing of the inflamed nodules and pustules, resolution of the painful symptoms, and an acceptable cosmetic outcome. Our case is paradigmatic of the potentiality of PDT to treat difficult and resistant-to-treatment lesions. Despite being time-consuming, this procedure has been demonstrated to be safe and well-tolerated. Lastly, the therapy is also well accepted by parents, due to its minimal invasiveness and mild side effects, compared to the other therapeutic options. |
| format | Article |
| id | doaj-art-1d3bba7ddd18422294799257d8214843 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-1d3bba7ddd18422294799257d82148432024-12-11T05:55:11ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-02-0145103893Photodynamic therapy for severe acneFederica Li Pomi0Mario Vaccaro1Lucia Peterle2Francesco Borgia3Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyCorresponding author.; Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyAcne is an inflammatory cutaneous disease affecting the pilosebaceous unit and hair follicles on the face, neck, back, and chest, with a typical onset in adolescence and, in some cases, persisting into adulthood. Systemic treatments with antibiotics or isotretinoin present many limitations, like antimicrobial resistance phenomena and teratogenicity, which appear more relevant in the pediatric population, both for the treatment-related risks and for the reticence of the parents. Photodynamic therapy (PDT) has already shown encouraging results in the treatment of acne in adult patients, with good aesthetic results compared to other therapies and few side effects. However, its use is still not standardized in the pediatric population. On this topic, we report our experience with PDT in a young patient affected by dorsal acne. After five sessions of ALA-PDT at monthly intervals, a remarkable improvement of the lesions was observed, with the healing of the inflamed nodules and pustules, resolution of the painful symptoms, and an acceptable cosmetic outcome. Our case is paradigmatic of the potentiality of PDT to treat difficult and resistant-to-treatment lesions. Despite being time-consuming, this procedure has been demonstrated to be safe and well-tolerated. Lastly, the therapy is also well accepted by parents, due to its minimal invasiveness and mild side effects, compared to the other therapeutic options.http://www.sciencedirect.com/science/article/pii/S1572100023006208AcnePhotodynamic therapyPDTChildAdolescenceALA |
| spellingShingle | Federica Li Pomi Mario Vaccaro Lucia Peterle Francesco Borgia Photodynamic therapy for severe acne Photodiagnosis and Photodynamic Therapy Acne Photodynamic therapy PDT Child Adolescence ALA |
| title | Photodynamic therapy for severe acne |
| title_full | Photodynamic therapy for severe acne |
| title_fullStr | Photodynamic therapy for severe acne |
| title_full_unstemmed | Photodynamic therapy for severe acne |
| title_short | Photodynamic therapy for severe acne |
| title_sort | photodynamic therapy for severe acne |
| topic | Acne Photodynamic therapy PDT Child Adolescence ALA |
| url | http://www.sciencedirect.com/science/article/pii/S1572100023006208 |
| work_keys_str_mv | AT federicalipomi photodynamictherapyforsevereacne AT mariovaccaro photodynamictherapyforsevereacne AT luciapeterle photodynamictherapyforsevereacne AT francescoborgia photodynamictherapyforsevereacne |