Tarlatamab and the Future of Immunotherapy: A New Approach to Small Cell Lung Cancer

Tarlatamab and the Future of Immunotherapy: A New Approach to Small Cell Lung Cancer

Saved in:

Bibliographic Details
Main Authors:	Raza Ur Rehman, MBBS, Ahmad Furqan Anjum, MBBS, Rida Fatima, MBBS
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Current Therapeutic Research
Subjects:	Bispecific T-cell engager DLL3 protein FDA approval Immunotherapy Small cell Lung cancer (SCLC) Tarlatamab
Online Access:	http://www.sciencedirect.com/science/article/pii/S0011393X24000432
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A year in review: new treatments and expanded indications in dermatology in 2024
by: Lauren N. McGrath, et al.
Published: (2025-12-01)

Impact of DLL3 Expression as Prognostic Factor in Extensive Stage of Small Cell Lung Cancer Treated With First‐Line Chemotherapy
by: Hohyung Nam, et al.
Published: (2025-01-01)

First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study
by: Laura Moliner, MD, et al.
Published: (2025-01-01)

Effective cancer immunotherapy combining mRNA-encoded bispecific antibodies that induce polyclonal T cell engagement and PD-L1-dependent 4-1BB costimulation
by: Oana Hangiu, et al.
Published: (2025-01-01)

Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment
by: Rahul Navab, et al.
Published: (2025-01-01)

A comprehensive overview of selective and novel fibroblast growth factor receptor inhibitors as a potential anticancer modality
by: Jain Nem Kumar, et al.
Published: (2024-03-01)

Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer
by: Lijuan Qin, et al.
Published: (2025-02-01)

Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC
by: Yujie Hao, et al.
Published: (2025-01-01)

Comparison of the Efficacy and Safety of PD‐1/PD‐L1 Inhibitors in the Treatment of Small Cell Lung Cancer
by: Qichen Zhang, et al.
Published: (2025-01-01)

Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma
by: Zihao Sun, et al.
Published: (2025-01-01)

Structural insights into antibody-based immunotherapy for hepatocellular carcinoma
by: Masaud Shah, et al.
Published: (2025-01-01)

Sinonasal small-cell carcinoma combined concurrently with small-cell lung carcinoma: case report and literature review
by: Rencui Quan, et al.
Published: (2025-01-01)

A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy
by: Gerhard Frey, et al.
Published: (2024-12-01)

Bibliometric insight into neoadjuvant immunotherapy in non-small cell lung cancer: trends, collaborations, and future avenues
by: Pengliang Xu, et al.
Published: (2025-02-01)

Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces
by: W. van der Wulp, et al.
Published: (2024-12-01)

The first case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer: case report and literature review
by: Tianxiao Fu, et al.
Published: (2025-01-01)

Identification of novel anti-CD16a antibody clones for the development of effective natural killer cell engagers
by: Bill Liao, et al.
Published: (2024-12-01)

Prognostic Impact of Adjuvant Immunotherapy in Patients With Resectable NSCLC After Neoadjuvant Chemoimmunotherapy: A Brief Report
by: Yichen Dong, MD, et al.
Published: (2025-01-01)

Partial Stereotactic Ablative Radiotherapy Boost Before Conventional Radiotherapy (P‐SABR) for Large (> 5 cm) Unresectable Stage III Nonsmall Cell Lung Cancer
by: Yun Bai, et al.
Published: (2025-01-01)

Engineered T cells secreting αB7-H3-αCD3 bispecific engagers for enhanced anti-tumor activity against B7-H3 positive multiple myeloma: a novel therapeutic approach
by: Punchita Rujirachaivej, et al.
Published: (2025-01-01)

Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression
by: Jianfeng Peng, et al.
Published: (2025-02-01)

Racial Differences in Systemic Immune Parameters in Individuals With Lung Cancer
by: Mitchell S. von Itzstein, MD, et al.
Published: (2025-01-01)

BLINATUMOMAB IN THE THERAPY OF ACUTE B-LYMPHOID LEUKEMIA
by: Ugo Testa, et al.
Published: (2024-08-01)

Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
by: Ammelie Svea Boje, et al.
Published: (2024-12-01)

Immunotherapy for Extensive-stage Small Cell Lung Cancer:  Research Progress and Future Perspectives
by: Yuling ZHONG, et al.
Published: (2024-11-01)

Pre-immunotherapy alters stereotactic ablative radiotherapy-induced systemic T cell responses in early-stage NSCLC
by: Chao Liu, et al.
Published: (2025-02-01)

First-line chemotherapy with tislelizumab for patients with extensive-stage small cell lung cancer: a cost-effectiveness analysis
by: Rong Long, et al.
Published: (2024-12-01)

Early Effects of Bronchoscopic Cryotherapy in Metastatic Non-Small Cell Lung Cancer Patients Receiving Immunotherapy: A Single-Center Prospective Study
by: Gediminas Vasiliauskas, et al.
Published: (2025-01-01)

Comprehensive analysis of telomere and aging-related signature for predicting prognosis and immunotherapy response in lung adenocarcinoma
by: Zhe Ye, et al.
Published: (2025-01-01)

Elevated LIF and JAK-STAT activation drive severe COVID-19 in myeloma patients receiving the BCMA-CD3 bispecific antibody Elranatamab
by: Ziping Li, et al.
Published: (2025-01-01)

The role of radiotherapy in small cell lung cancer: a new paradigm for the radiation oncologist
by: Paolo Borghetti, et al.
Published: (2025-01-01)

Natural killer cell engagers for cancer immunotherapy
by: Shahryar Khoshtinat Nikkhoi, et al.
Published: (2025-01-01)

Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review
by: Balsa Nobility Gustifante, et al.
Published: (2025-01-01)

Radiotherapy Combined with Immunotherapy and Chemotherapy Improves Prognosis and Demonstrates Synergistic Effects in Extensive-stage Small Cell Lung Cancer
by: Huaijun JI, et al.
Published: (2024-11-01)

Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma
by: Kai Zhang, et al.
Published: (2025-01-01)

Small cell lung cancer with EML4-ALK fusion: report of a case responding to ALK TKI and literature review
by: Mingyue Wang, et al.
Published: (2025-02-01)

Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis
by: Qiong Zhang, et al.
Published: (2025-01-01)

Progress in nanomedicine for sonodynamic immunotherapy of tumors
by: Ziyan Feng, et al.
Published: (2024-09-01)

A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion
by: Chongwei Xie, et al.
Published: (2025-03-01)

Brief report: impact of consolidation durvalumab on unresectable non-small cell lung cancer with driver mutations
by: Jason C.S. Ho, et al.
Published: (2024-01-01)