Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients
Head and neck squamous cell carcinoma (HNSCC) encompass cancers originating in the head and neck mucosal surfaces, including the oral cavity, pharynx, and larynx. Standard treatments involve surgery, radiation therapy, chemotherapy, or combinations thereof. Radiation therapy, targeting pharyngeal ca...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024003601 |
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| author | Sivakamavalli Jeyachandran |
| author_facet | Sivakamavalli Jeyachandran |
| author_sort | Sivakamavalli Jeyachandran |
| collection | DOAJ |
| description | Head and neck squamous cell carcinoma (HNSCC) encompass cancers originating in the head and neck mucosal surfaces, including the oral cavity, pharynx, and larynx. Standard treatments involve surgery, radiation therapy, chemotherapy, or combinations thereof. Radiation therapy, targeting pharyngeal cancer cells, is common but can damage critical structures, affecting quality of life (QoL). Dysphagia, xerostomia, speech difficulties, and pain are prevalent side effects. Research shows radiation dose correlates with severity of these effects; sparing healthy tissue reduces side effects. Advanced techniques like intensity-modulated radiation therapy (IMRT) and proton therapy offer precise tumor targeting, sparing normal tissues. Ongoing research aims to refine techniques for better long-term outcomes in HNSCC patients. |
| format | Article |
| id | doaj-art-1d05d250e5c2493096c65a03ee6bead1 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-1d05d250e5c2493096c65a03ee6bead12025-01-09T06:16:35ZengElsevierOral Oncology Reports2772-90602024-06-0110100514Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patientsSivakamavalli Jeyachandran0Lab in Biotechnology and Biosignal Transduction, Department of Orthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 77, IndiaHead and neck squamous cell carcinoma (HNSCC) encompass cancers originating in the head and neck mucosal surfaces, including the oral cavity, pharynx, and larynx. Standard treatments involve surgery, radiation therapy, chemotherapy, or combinations thereof. Radiation therapy, targeting pharyngeal cancer cells, is common but can damage critical structures, affecting quality of life (QoL). Dysphagia, xerostomia, speech difficulties, and pain are prevalent side effects. Research shows radiation dose correlates with severity of these effects; sparing healthy tissue reduces side effects. Advanced techniques like intensity-modulated radiation therapy (IMRT) and proton therapy offer precise tumor targeting, sparing normal tissues. Ongoing research aims to refine techniques for better long-term outcomes in HNSCC patients.http://www.sciencedirect.com/science/article/pii/S2772906024003601HNSCCProton therapyIMRTXerostomia |
| spellingShingle | Sivakamavalli Jeyachandran Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients Oral Oncology Reports HNSCC Proton therapy IMRT Xerostomia |
| title | Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients |
| title_full | Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients |
| title_fullStr | Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients |
| title_full_unstemmed | Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients |
| title_short | Interlink between pharyngeal radiation dose and long-term quality of life in HNSCC patients |
| title_sort | interlink between pharyngeal radiation dose and long term quality of life in hnscc patients |
| topic | HNSCC Proton therapy IMRT Xerostomia |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024003601 |
| work_keys_str_mv | AT sivakamavallijeyachandran interlinkbetweenpharyngealradiationdoseandlongtermqualityoflifeinhnsccpatients |