TM4SF4 is a diagnostic biomarker accelerating progression of papillary thyroid cancer via AKT pathway

TM4SF4 is a diagnostic biomarker accelerating progression of papillary thyroid cancer via AKT pathway

The incidence of papillary thyroid cancer (PTC) has been steadily rising, though the underlying mechanism remains unclear. This study aims to elucidate the biological role of TM4SF4 in the PTC progression. Our differential expression analysis indicated that TM4SF4 was significantly upregulated in PT...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lizhi Lin, Jialiang Wen, Tiansheng Xu, Yuhao Si
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Cancer Biology & Therapy
Subjects:	TM4SF4 diagnostic biomarker papillary thyroid cancer AKT
Online Access:	https://www.tandfonline.com/doi/10.1080/15384047.2024.2424570
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5
by: Semi Kim, et al.
Published: (2014-03-01)

TGFBR3 inhibits progression of papillary thyroid cancer by inhibiting the PI3K/AKT pathway and EMT
by: Hanrong Zhang, et al.
Published: (2024-11-01)

Deep metabolic phenotyping of humans with protein-altering variants in TM6SF2 using a genome-first approach
by: Helen Ye Rim Huang, et al.
Published: (2025-01-01)

Efficient high-power 2.3 μm continuous-wave laser operation of diffusion-bonded composite YVO4/Tm:GdVO4 crystals
by: Xiaoxu Yu, et al.
Published: (2024-01-01)

Hidden in Plain Sight: Incidental Diagnosis of Metastatic Papillary Thyroid Microcarcinoma Without Radiologically Apparent Thyroid Tumor
by: Natalie Rivera Vargas, MD, et al.
Published: (2025-01-01)

Thyroid Hemiagenesis: An Incidental Discovery during Treatment for Papillary Thyroid Carcinoma
by: Chang Haur Lee, et al.
Published: (2024-11-01)

Thyroid Papillary Microcarcinoma - Carcinoma with Clinically Benign Behaviour
by: Hitesh R Singhavi, et al.
Published: (2023-12-01)

Correlationship between total proteins SUMOylation and papillary thyroid carcinoma in males
by: WU Qiao, LIU Wei, ZHENG Jiaojiao, WANG Cong, AI Zhilong
Published: (2024-07-01)

Clinical Treatment Status of Papillary Thyroid Microcarcinoma
by: Liu Tong, Meng Kexin, Zhu Ying, Fan Fengjing, Wang Bei
Published: (2025-03-01)

Diagnosis and thermal ablation of papillary thyroid microcarcinoma
by: QUAN Yinglan, LI Ning
Published: (2024-12-01)

Aplastic anemia in a patient with papillary thyroid carcinoma complicated with Hashimoto’s thyroiditis: a case report
by: Fei Wu, et al.
Published: (2025-01-01)

Preoperative ultrasound-guided injection of nanocarbon for central lymph node dissection in patients with papillary thyroid carcinoma
by: Ying Wang, et al.
Published: (2024-11-01)

Synchronous occurrence of papillary thyroid carcinoma and solitary fibrous tumor of the thyroid: a case report
by: Maissa Ben Thayer, et al.
Published: (2024-12-01)

Evaluation of the Her-2/neu value in papillary thyroid carcinoma and its relation to histopathological prognostic findings
by: Amin Azarnoosh, et al.
Published: (2024-01-01)

Worse survival and higher rates of relapse in U.S. Armenians with papillary thyroid cancer
by: Karen Tsai, et al.
Published: (2024-12-01)

Optimizing surgical outcomes in papillary thyroid carcinoma with Hashimoto’s Thyroiditis: a retrospective comparative study of unilateral and total thyroidectomy
by: Xiaoyong Wen, et al.
Published: (2024-12-01)

Patterns of regional recurrence in papillary thyroid cancer patients with lateral neck metastases undergoing neck dissection
by: Jason J. Xu, et al.
Published: (2017-05-01)

THE USE OF ARTIFICIAL INTELLIGENCE IN THE THERAPEUTIC MANAGEMENT OF PAPILLARY THYROID MICROCARCINOMA: A RANDOMIZED CONTROLLED TRIAL PROTOCOL
by: Ramona Elena Teiu, et al.
Published: (2024-12-01)

Radiofrequency Ablation for Recurrent Papillary Thyroid Carcinoma at the Central Compartment Node: A Case Report
by: Le Thi My, et al.

Comparison of clinicopathological characteristics and prognosis between primary squamous cell carcinoma of the thyroid and squamous cell carcinoma combined with papillary thyroid carcinoma
by: Wanyun Yan, et al.
Published: (2025-01-01)

Effects of Fibroblast Growth Factor 21 Serum Level on Clinicopathological Findings in Papillary Thyroid Carcinoma
by: Seyedarad Mosalamiaghili, et al.
Published: (2025-10-01)

Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location
by: Haoyu Jing, et al.
Published: (2024-12-01)

Comprehensive analysis of clinicopathologic and prognostic features in locally advanced thyroid papillary cancer
by: Liang Jiwang, et al.
Published: (2025-03-01)

POSTRADIAL SIALOZOADENITIS IN PATIENTS WITH PAPILLARY CARCINOMA OF THE THYROID GLAND
by: V. A. Kovalenko, et al.
Published: (2015-02-01)

Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital—
by: Yasuhiro Ito, et al.
Published: (2024-01-01)

Papillary carcinoma thyroid with fibromatosis/fasciitis-like stroma: Report of a rare case with review of literature
by: Nischitha Suvarna, et al.
Published: (2024-07-01)

Association of the Preoperative Controlling Nutritional Status (CONUT) Score with Clinicopathological Characteristics in Patients with Papillary Thyroid Carcinoma
by: Doohwa Kim, et al.
Published: (2024-12-01)

mutations and aggressive histopathologic characteristics of radioiodine-refractory papillary thyroid cancer
by: Ju Yeon Pyo, et al.
Published: (2024-11-01)

Combined detection of inflammatory proteins is beneficial for diagnosing the papillary thyroid carcinoma and nodular goiter
by: Yongqin Pan, et al.
Published: (2024-09-01)

FBP1 over-expression suppresses HIF-1α in papillary thyroid cancer
by: Huashui Li, et al.
Published: (2024-11-01)

Thyroid antibodies in Hashimoto’s thyroiditis patients are positively associated with inflammation and multiple symptoms
by: Jiaomei Li, et al.
Published: (2024-11-01)

Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma
by: Wei An, et al.
Published: (2025-02-01)

Thyroid concurrent papillary carcinoma and occult follicular carcinoma: Report of a rare case and discussion of surgical management strategies
by: Jingran Wang, et al.
Published: (2025-01-01)

A multivariable model of ultrasound and biochemical parameters for predicting high-volume lymph node metastases of papillary thyroid carcinoma with Hashimoto’s thyroiditis
by: Xiao-hui Liu, et al.
Published: (2025-01-01)

Correlation analysis of Hashimoto’s thyroiditis with papillary thyroid carcinoma occurrence and its central lymph node metastasis: a single center experience
by: Kang Sun, et al.
Published: (2025-02-01)

Prognosis of invasive encapsulated follicular variant and classical papillary thyroid carcinoma: a propensity score-matched study using the SEER database
by: Shuai Jin, et al.
Published: (2025-01-01)

Hubungan Ekspresi Sodium Iodide Symporter dengan Varian Histopatologi dan Stadium Papillary Thyroid Carcinoma
by: Rini Purnama Sari, et al.
Published: (2024-02-01)

Radiofrequency ablation for solitary T1N0M0 papillary thyroid carcinoma in the danger triangle area: a preliminary analysis
by: Dan-ling Zhang, et al.
Published: (2024-12-01)

Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis
by: Bin Wang, et al.
Published: (2019-08-01)

Spatial and Single‐Cell Transcriptomics Unraveled Spatial Evolution of Papillary Thyroid Cancer
by: Guangzhe Zheng, et al.
Published: (2025-01-01)