Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control

Abstract Most synthetic self-assemblies grow indefinitely into size-unlimited structures, whereas some biological self-assemblies autonomously regulate their size and shape. One mechanism of such self-regulation arises from the chirality of building blocks, inducing their mutual twisting that is inc...

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Main Authors: Shuxu Wang, Louis Kang, Péter Salamon, Xiang Wang, Noriyuki Uchida, Fumito Araoka, Takuzo Aida, Zvonimir Dogic, Yasuhiro Ishida
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54217-x
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author Shuxu Wang
Louis Kang
Péter Salamon
Xiang Wang
Noriyuki Uchida
Fumito Araoka
Takuzo Aida
Zvonimir Dogic
Yasuhiro Ishida
author_facet Shuxu Wang
Louis Kang
Péter Salamon
Xiang Wang
Noriyuki Uchida
Fumito Araoka
Takuzo Aida
Zvonimir Dogic
Yasuhiro Ishida
author_sort Shuxu Wang
collection DOAJ
description Abstract Most synthetic self-assemblies grow indefinitely into size-unlimited structures, whereas some biological self-assemblies autonomously regulate their size and shape. One mechanism of such self-regulation arises from the chirality of building blocks, inducing their mutual twisting that is incompatible with their long-range ordered packing and thus halts the assembly’s growth at a certain stage. This self-regulation occurs robustly in thermodynamic equilibrium rather than kinetic trapping, and therefore is attractive yet elusive. Until now, studies of self-regulating assemblies have focused on non-responsive systems, whose equilibrium point and corresponding size and shape are hardly changeable. Here, we demonstrate a stimuli-responsive, self-regulating assembly. This assembly consists of chiral and magnetically orientable nanorods, where the effective chirality can be changed by balancing chirality-induced twisting and magnet-induced flattening between nanorods. Consequently, the strength of self-regulation in the assembly is modulable by magnetic field intensity, allowing robust, tunable, and reversible control of its size and shape. Our strategy would provide more biomimetic materials with precision and responsiveness.
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institution Kabale University
issn 2041-1723
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publishDate 2024-11-01
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spelling doaj-art-1cbe5206ce8f44d3a3ee404b01d7333f2024-11-17T12:36:56ZengNature PortfolioNature Communications2041-17232024-11-0115111110.1038/s41467-024-54217-xStimuli-responsive self-regulating assembly of chiral colloids for robust size and shape controlShuxu Wang0Louis Kang1Péter Salamon2Xiang Wang3Noriyuki Uchida4Fumito Araoka5Takuzo Aida6Zvonimir Dogic7Yasuhiro Ishida8RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoRIKEN Center for Brain Science, 2-1 Hirosawa, WakoHUN-REN Wigner Research Centre for Physics, P.O. Box 49RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoRIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoRIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoRIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoDepartment of Physics, University of California at Santa BarbaraRIKEN Center for Emergent Matter Science, 2-1 Hirosawa, WakoAbstract Most synthetic self-assemblies grow indefinitely into size-unlimited structures, whereas some biological self-assemblies autonomously regulate their size and shape. One mechanism of such self-regulation arises from the chirality of building blocks, inducing their mutual twisting that is incompatible with their long-range ordered packing and thus halts the assembly’s growth at a certain stage. This self-regulation occurs robustly in thermodynamic equilibrium rather than kinetic trapping, and therefore is attractive yet elusive. Until now, studies of self-regulating assemblies have focused on non-responsive systems, whose equilibrium point and corresponding size and shape are hardly changeable. Here, we demonstrate a stimuli-responsive, self-regulating assembly. This assembly consists of chiral and magnetically orientable nanorods, where the effective chirality can be changed by balancing chirality-induced twisting and magnet-induced flattening between nanorods. Consequently, the strength of self-regulation in the assembly is modulable by magnetic field intensity, allowing robust, tunable, and reversible control of its size and shape. Our strategy would provide more biomimetic materials with precision and responsiveness.https://doi.org/10.1038/s41467-024-54217-x
spellingShingle Shuxu Wang
Louis Kang
Péter Salamon
Xiang Wang
Noriyuki Uchida
Fumito Araoka
Takuzo Aida
Zvonimir Dogic
Yasuhiro Ishida
Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
Nature Communications
title Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
title_full Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
title_fullStr Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
title_full_unstemmed Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
title_short Stimuli-responsive self-regulating assembly of chiral colloids for robust size and shape control
title_sort stimuli responsive self regulating assembly of chiral colloids for robust size and shape control
url https://doi.org/10.1038/s41467-024-54217-x
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