Effects of opioid-free anesthesia combined with iliofascial nerve block on perioperative neurocognitive deficits in elderly patients undergoing hip fracture surgery: study protocol for a prospective, multicenter, parallel-group, randomized controlled trial

Effects of opioid-free anesthesia combined with iliofascial nerve block on perioperative neurocognitive deficits in elderly patients undergoing hip fracture surgery: study protocol for a prospective, multicenter, parallel-group, randomized controlled trial

Abstract Background Perioperative neurocognitive dysfunction (PND), a prevalent complication affecting elderly surgical patients, poses substantial challenges to postoperative rehabilitation and long-term functional independence. Despite growing awareness of its clinical significance, current eviden...

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Main Authors: Tong Zhi, Shirong Wei, Jiao Kuang, Sitong Zhou, Danhong Yu, Tesheng Gao, Long Lei, Chengfei Xu, Liang Cheng, Qinghe Zhou, Ming Yao, Huadong Ni
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Trials
Subjects:
Opioid-free anesthesia
Iliofascial nerve block
Perioperative neurocognitive disorders
Elderly patients
Hip fracture surgery
Online Access:https://doi.org/10.1186/s13063-025-08828-4
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https://doi.org/10.1186/s13063-025-08828-4

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