Assessment of patient satisfaction and adherence to treatment with IOP-lowering medication in an innovative OSD bottle

<p> D.P. Novikov, E.S. Kuznetsova </p> <p> Diagnostic Center No. 7 (Ocular), St. Petersburg, Russian Federation </p> <p> <b>Background: </b>a significant proportion of patients with glaucoma require two or three IOP-lowering medications to achieve the t...

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Bibliographic Details
Main Authors: D.P. Novikov, E.S. Kuznetsova
Format: Article
Language:Russian
Published: Prime-Media 2023-11-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/075/0vl6a7ludsl6zybaphjve4mb5hpcpu1i.pdf
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Summary:<p> D.P. Novikov, E.S. Kuznetsova </p> <p> Diagnostic Center No. 7 (Ocular), St. Petersburg, Russian Federation </p> <p> <b>Background: </b>a significant proportion of patients with glaucoma require two or three IOP-lowering medications to achieve the target IOP. Factors that improve adherence to treatment include fixed-dose combinations (FDC) and preservative-free formulations. Good tolerability of long-term treatment and precise dosing are important prerequisites for the efficacy of glaucoma treatment. Recently, the ophthalmological armamentarium was replenished with preservative-free dorzolamide/timolol FDC containing sodium hyaluronate (Dorzial plus), thereby increasing adherence to prescribed therapy. </p> <p> <b>Aim: </b>to assess subjective difficulties in using the drug in an OSD bottle and to identify the most significant factors affecting treatment comfort and adherence to treatment. </p> <p> <b>Patients and Methods: </b>a questionnaire consisting of 9 questions was developed. Patients were surveyed in the outpatient setting. The survey involved 43 patients (32 women and 11 men). Questionnaires were completed anonymously without specifying personal data after 1 month of using the study drug. </p> <p> <b>Results and Discussion: </b>treatment comfort was rated "satisfied” and “very satisfied" by more than 90% of the respondents. In addition, more than 90% successfully dealt with drug dosing (1 drop from the OSD bottle). Difficulties in applying force when pressing the OSD bottle were rare, although a positive assessment of drug characteristics prevailed. When asked about continuing therapy, most respondents answered that they wanted to continue treatment with the prescribed drug. </p> <p> <b>Conclusion: </b>the survey demonstrated that Dorzial Plus has the necessary range of characteristics to ensure a high level of patient satisfaction and adherence to treatment. </p> <p> <b>Keywords: </b>adherence to treatment, primary open-angle glaucoma, OSD bottle, dorzolamide/timolol fixed-dose combination, preservative-free therapy, treatment comfort. </p> <p> <b>For citation: </b>Novikov D.P., Kuznetsova E.S. Assessment of patient satisfaction and adherence to treatment with IOP-lowering medication in an innovative OSD bottle. Russian Journal of Clinical Ophthalmology. 2023;23(4):192–196 (in Russ.). DOI: 10.32364/2311-7729-2023-23-4-3. </p>
ISSN:2311-7729
2619-1571