Upregulation of inhibitor of DNA binding 1 and 3 is important for efficient thermogenic response in human adipocytes

Upregulation of inhibitor of DNA binding 1 and 3 is important for efficient thermogenic response in human adipocytes

Abstract Brown and beige adipocytes can be activated by β-adrenergic agonist via cAMP-dependent signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes, we found that dibutyryl-cAMP, which can mimic in vivo stimulation of browning and thermogenesis, enhanced the expre...

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Main Authors: Rini Arianti, Boglárka Ágnes Vinnai, Rahaf Alrifai, Gyath Karadsheh, Yousif Qais Al-Khafaji, Szilárd Póliska, Ferenc Győry, László Fésüs, Endre Kristóf
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Adipocytes
Browning
Thermogenesis
Adrenergic stimulation
ID1
ID3
Online Access:https://doi.org/10.1038/s41598-024-79634-2
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