Optimization of layering technique and secondary structure analysis during the formulation of nanoparticles containing lysozyme by quality by design approach.

In our study, core-shell nanoparticles containing lysozyme were formulated with precipitation and layering self-assembly. Factorial design (DoE) was applied by setting the process parameters during the preparation with Quality by Design (QbD) approach. The factors were the concentration of lysozyme...

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Bibliographic Details
Main Authors: Katalin Kristó, Reihaneh Manteghi, Yousif H-E Y Ibrahim, Ditta Ungor, Edit Csapó, Dániel Berkesi, Zoltán Kónya, Ildikó Csóka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0260603&type=printable
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