Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer

Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer

Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human subjects, we developed a liquid biopsy signature ba...

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Bibliographic Details
Main Authors: Jianying Xu, Wenjie Shi, Yi Zhu, Chao Zhang, Julia Nagelschmitz, Maximilian Doelling, Sara Al-Madhi, Ujjwal Mukund Mahajan, Maciej Pech, Georg Rose, Roland Siegfried Croner, Guoliang Zheng, Christoph Kahlert, Ulf Dietrich Kahlert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-08-01
Series:eLife
Subjects:
liquid biopsy
pancreatic cancer
radiomics
machine learning
extracellular vesicles
microRNA
Online Access:https://elifesciences.org/articles/103737
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