Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes

Enterobacteriaceae are Gram-negative bacteria that have many mechanisms to survive in contaminated environments. Klebsiella pneumoniae is one of them that express efflux pump genes in the presence of heavy metals, like AcrAb and OqxA genes. The purpose of this study is to investigate the relationsh...

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Main Authors: Eman Abbas Muhsin, Maitham A. Sultan, Esam Abdalraheem Abdalwahed, Shahrazad A. Khalaf
Format: Article
Language:English
Published: Corporation of Research and Industrial Development 2024-06-01
Series:Iraqi Journal of Industrial Research
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Online Access:http://ijoir.gov.iq/ijoir/index.php/jou/article/view/440
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author Eman Abbas Muhsin
Maitham A. Sultan
Esam Abdalraheem Abdalwahed
Shahrazad A. Khalaf
author_facet Eman Abbas Muhsin
Maitham A. Sultan
Esam Abdalraheem Abdalwahed
Shahrazad A. Khalaf
author_sort Eman Abbas Muhsin
collection DOAJ
description Enterobacteriaceae are Gram-negative bacteria that have many mechanisms to survive in contaminated environments. Klebsiella pneumoniae is one of them that express efflux pump genes in the presence of heavy metals, like AcrAb and OqxA genes. The purpose of this study is to investigate the relationship between the existence of efflux pump genes in K. pneumoniae, and heavy metal contamination in the Tigris River. By comparing important indicators to World Health Organization (WHO) criteria, this study aims to analyze the river's water quality. It focuses on detection of cadmium (Cd), lead (Pb), nickel (Ni), arsenic (As), mercury (Hg), iron (Fe), and cobalt (Co). Fifteen samples of the Tigris River near the Al-Dura project of water remediation were obtained and cultured on selective media, and the water quality parameters, like TSS, TDS, TH, pH, turbidity, EC, BOD, COD, OD, TOC, and heavy metals, were estimated. Bacterial DNA was extracted, then efflux genes were detected with the presence of heavy metals in the tested samples. Results illustrated that K. pneumoniae gave positive results in nine of the total fifteen samples, and the water quality parameters were within the normal ranges, except for elevated levels of DO and TOC, and decreased levels of BOD and COD, with a significant relationship among heavy metal levels with both AcrAB and OqxA genes at a significance level of p ≤ 0.05.
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institution Kabale University
issn 2788-712X
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publishDate 2024-06-01
publisher Corporation of Research and Industrial Development
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series Iraqi Journal of Industrial Research
spelling doaj-art-1c2ec9312a024f338c82e33a8d7283e22024-12-15T05:02:28ZengCorporation of Research and Industrial DevelopmentIraqi Journal of Industrial Research2788-712X2024-06-0111110.53523/ijoirVol11I1ID440440Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump GenesEman Abbas Muhsin0Maitham A. Sultan1Esam Abdalraheem Abdalwahed2Shahrazad A. Khalaf3Environment, Water, and Renewable Energy Directorate, Ministry of Science and Technology, IraqEnvironment, Water, and Renewable Energy Directorate, Ministry of Science and Technology, IraqEnvironment, Water, and Renewable Energy Directorate, Ministry of Science and Technology, IraqBiotechnology Department, College of Science, Diyala University, Iraq Enterobacteriaceae are Gram-negative bacteria that have many mechanisms to survive in contaminated environments. Klebsiella pneumoniae is one of them that express efflux pump genes in the presence of heavy metals, like AcrAb and OqxA genes. The purpose of this study is to investigate the relationship between the existence of efflux pump genes in K. pneumoniae, and heavy metal contamination in the Tigris River. By comparing important indicators to World Health Organization (WHO) criteria, this study aims to analyze the river's water quality. It focuses on detection of cadmium (Cd), lead (Pb), nickel (Ni), arsenic (As), mercury (Hg), iron (Fe), and cobalt (Co). Fifteen samples of the Tigris River near the Al-Dura project of water remediation were obtained and cultured on selective media, and the water quality parameters, like TSS, TDS, TH, pH, turbidity, EC, BOD, COD, OD, TOC, and heavy metals, were estimated. Bacterial DNA was extracted, then efflux genes were detected with the presence of heavy metals in the tested samples. Results illustrated that K. pneumoniae gave positive results in nine of the total fifteen samples, and the water quality parameters were within the normal ranges, except for elevated levels of DO and TOC, and decreased levels of BOD and COD, with a significant relationship among heavy metal levels with both AcrAB and OqxA genes at a significance level of p ≤ 0.05. http://ijoir.gov.iq/ijoir/index.php/jou/article/view/440AcrAbOqxAKlebsiella pneumoniaHeavy metals
spellingShingle Eman Abbas Muhsin
Maitham A. Sultan
Esam Abdalraheem Abdalwahed
Shahrazad A. Khalaf
Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
Iraqi Journal of Industrial Research
AcrAb
OqxA
Klebsiella pneumonia
Heavy metals
title Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
title_full Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
title_fullStr Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
title_full_unstemmed Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
title_short Detection of some Biological Parameters and Heavy Metals Presence in Tigris River Water by Novel Designed Bacterial Efflux Pump Genes
title_sort detection of some biological parameters and heavy metals presence in tigris river water by novel designed bacterial efflux pump genes
topic AcrAb
OqxA
Klebsiella pneumonia
Heavy metals
url http://ijoir.gov.iq/ijoir/index.php/jou/article/view/440
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