Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses

Bread wheat (Triticum aestivum) is a vital global staple food, providing 30 % of the world's caloric intake and nutritional needs. It was domesticated over 10,000 years ago and adapted to various biotic and abiotic stresses, crucial for maintaining food security. Modern research highlights the...

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Main Authors: Zhiwei Wang, Aimen Shafique, Bofeng Yu, Badr Alharthi, Naushad Ali, Muhammad Salman Mubarik, Hafiz Saeed ur Rehman, Rashid Iqbal, Farrukh Azeem, Hongxing Xu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Plant Stress
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667064X24002987
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author Zhiwei Wang
Aimen Shafique
Bofeng Yu
Badr Alharthi
Naushad Ali
Muhammad Salman Mubarik
Hafiz Saeed ur Rehman
Rashid Iqbal
Farrukh Azeem
Hongxing Xu
author_facet Zhiwei Wang
Aimen Shafique
Bofeng Yu
Badr Alharthi
Naushad Ali
Muhammad Salman Mubarik
Hafiz Saeed ur Rehman
Rashid Iqbal
Farrukh Azeem
Hongxing Xu
author_sort Zhiwei Wang
collection DOAJ
description Bread wheat (Triticum aestivum) is a vital global staple food, providing 30 % of the world's caloric intake and nutritional needs. It was domesticated over 10,000 years ago and adapted to various biotic and abiotic stresses, crucial for maintaining food security. Modern research highlights the interconnected signalling pathways for both biotic and abiotic stresses, that help wheat cope with these biotic and abiotic stresses. Identification of regulatory proteins is essential for advanced wheat breeding. In the current study, 32 DRP genes in wheat were identified that are evenly distributed on all the chromosomes with the presence of conserved dynamin-related domain. PPI analysis reveals that the TaDRP2-like genes interact with each other. Gene ontology analysis indicating the significant involvement of DRP genes in various processes including GTPase activity, binding, microtubule binding, and various cells including membrane (GO:0,016,020), cytoplasm (GO:0,005,737), microtubule (GO:0,005,874). Cis-element prediction reveals the enrichment of total 2006 elements including CAAT-box (390), TATA-box (327), MYB (131), and ABRE (93). Transcriptome and qRT-PCR analyses showed that TaDRP1-like, TaDRP2-like, and TaDRP3-like genes are highly expressed in roots, stems, leaves, and spikes, with lower expression in grains. Notably, TaDRP1D-B emerged as a potential candidate for enhancing resistance to powdery mildew, rust, drought, and heat stress. Furthermore, the interaction compatibility of TaDRP1D-B with PPA2 further confirms the potential role in regulating plant disease response. This research provides a foundation for developing strategies to enhance wheat resilience, directly contributing to global food security.
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spelling doaj-art-1c2d99b17252400c9909071238b3ffa02024-12-19T11:02:04ZengElsevierPlant Stress2667-064X2024-12-0114100645Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stressesZhiwei Wang0Aimen Shafique1Bofeng Yu2Badr Alharthi3Naushad Ali4Muhammad Salman Mubarik5Hafiz Saeed ur Rehman6Rashid Iqbal7Farrukh Azeem8Hongxing Xu9School of Agriculture, Henan Institute of Science and Technology, Xinxiang 453000, ChinaSchool of life sciences, Henan University, Kaifeng, Henan 475004, China; Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, PakistanSchool of Agriculture, Henan Institute of Science and Technology, Xinxiang 453000, ChinaDepartment of Biology, University College of Al Khurmah, Taif University, PO. Box 11099, Taif 21944, Saudi ArabiaDepartment of Plant Breeding and Genetics, The University of Haripur, 22620 Haripur, Khyber Pakhtunkhwa, PakistanDepartment of Biotechnology, University of Narowal, PakistanAyub Agricultural Research Institute, Faisalabad, PakistanDepartment of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, 63100 Pakistan; Department of Life Sciences, Western Caspian University, Baku, AzerbaijanDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan; Corresponding authors.School of life sciences, Henan University, Kaifeng, Henan 475004, China; Corresponding authors.Bread wheat (Triticum aestivum) is a vital global staple food, providing 30 % of the world's caloric intake and nutritional needs. It was domesticated over 10,000 years ago and adapted to various biotic and abiotic stresses, crucial for maintaining food security. Modern research highlights the interconnected signalling pathways for both biotic and abiotic stresses, that help wheat cope with these biotic and abiotic stresses. Identification of regulatory proteins is essential for advanced wheat breeding. In the current study, 32 DRP genes in wheat were identified that are evenly distributed on all the chromosomes with the presence of conserved dynamin-related domain. PPI analysis reveals that the TaDRP2-like genes interact with each other. Gene ontology analysis indicating the significant involvement of DRP genes in various processes including GTPase activity, binding, microtubule binding, and various cells including membrane (GO:0,016,020), cytoplasm (GO:0,005,737), microtubule (GO:0,005,874). Cis-element prediction reveals the enrichment of total 2006 elements including CAAT-box (390), TATA-box (327), MYB (131), and ABRE (93). Transcriptome and qRT-PCR analyses showed that TaDRP1-like, TaDRP2-like, and TaDRP3-like genes are highly expressed in roots, stems, leaves, and spikes, with lower expression in grains. Notably, TaDRP1D-B emerged as a potential candidate for enhancing resistance to powdery mildew, rust, drought, and heat stress. Furthermore, the interaction compatibility of TaDRP1D-B with PPA2 further confirms the potential role in regulating plant disease response. This research provides a foundation for developing strategies to enhance wheat resilience, directly contributing to global food security.http://www.sciencedirect.com/science/article/pii/S2667064X24002987DRPPPA2Powdery mildewRustHeatWheat breeding
spellingShingle Zhiwei Wang
Aimen Shafique
Bofeng Yu
Badr Alharthi
Naushad Ali
Muhammad Salman Mubarik
Hafiz Saeed ur Rehman
Rashid Iqbal
Farrukh Azeem
Hongxing Xu
Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
Plant Stress
DRP
PPA2
Powdery mildew
Rust
Heat
Wheat breeding
title Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
title_full Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
title_fullStr Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
title_full_unstemmed Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
title_short Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
title_sort characterization of dynamin related proteins drp in bread wheat tadrp1d b as regulator of biotic and abiotic stresses
topic DRP
PPA2
Powdery mildew
Rust
Heat
Wheat breeding
url http://www.sciencedirect.com/science/article/pii/S2667064X24002987
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