Deep anterior chamber depth may be a risk factor for axial length growth in children

ObjectiveTo investigate and evaluate the progression of myopia and associated factors of axial length (AL) growth among children in Chongqing.MethodsThis six-month prospective study was conducted on students in grades 1 to 8 at a school in Chongqing, China. All participants underwent a standard opht...

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Main Authors: Huijie Cao, Yongguo Xiang, Hong Cheng, Kexin Sun, Shijie Zheng, Miaomiao Du, Ning Gao, Tong Zhang, Xin Yang, Jiuyi Xia, Wenjuan Wan, Ke Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1489989/full
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Summary:ObjectiveTo investigate and evaluate the progression of myopia and associated factors of axial length (AL) growth among children in Chongqing.MethodsThis six-month prospective study was conducted on students in grades 1 to 8 at a school in Chongqing, China. All participants underwent a standard ophthalmologic examination including uncorrected visual acuity (UCVA), noncycloplegic refraction, AL, and corneal topography in March 2023. Six months later, the above examinations were repeated to obtain follow-up data. Visual habits questionnaire was gained to analyze the correlation between the AL growth and vision-related behavior.ResultsA total of 417 students from Chongqing were enrolled in this study. The myopia prevalence was higher in follow-up (38.6%) than in baseline (33.3%) and the AL was longer in follow-up than in baseline (23.69 ± 1.03 mm vs. 23.57 ± 1.03 mm, p < 0.001). The anterior chamber depth (ACD) in students with AL growth greater than or equal to 0.2 mm (3.16 ± 0.23 mm) was deeper than that in students with AL growth less than or equal to 0.05 mm (3.02 ± 0.28 mm, p = 0.001), lens thickness (LT) was thinner (3.29 ± 0.10 mm vs. 3.33 ± 0.10 mm, p = 0.004). Furthermore, ACD was positively correlated with AL growth. (r = 0.181, p < 0.001).ConclusionCompared to SE, AL serves as a more sensitive indicator for monitoring myopia progression. ACD was positively correlated with AL growth, and deeper ACD may be contributed to longer AL growth.
ISSN:2296-858X