Albiflorin inhibits inflammation to improve liver fibrosis by targeting the CXCL12/CXCR4 axis in mice

Albiflorin inhibits inflammation to improve liver fibrosis by targeting the CXCL12/CXCR4 axis in mice

Liver fibrosis is a common pathological feature of chronic hepatic injury that currently lacks effective therapeutic interventions. Albiflorin (ALB), a pinane-type monoterpene derived from Paeonia lactiflora Pall, has notable anti-inflammatory and hepatoprotective effects. However, the potential rol...

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Bibliographic Details
Main Authors: Lingjie Meng, Huijing Lv, Anli Liu, Qian Cao, Xinyi Du, Chengjin Li, Qinggui Li, Qingqing Luo, Yi Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
albiflorin
CXCL12/CXCR4 axis
liver fibrosis
inflammation
combination therapeutic
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1577201/full
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