Chromosome drives via CRISPR-Cas9 in yeast
Abstract Self-propagating drive systems are capable of causing non-Mendelian inheritance. Here, we report a drive system in yeast referred to as a chromosome drive that eliminates the target chromosome via CRISPR-Cas9, enabling the transmission of the desired chromosome. Our results show that the en...
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| Main Authors: | Hui Xu, Mingzhe Han, Shiyi Zhou, Bing-Zhi Li, Yi Wu, Ying-Jin Yuan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18222-0 |
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