Library-based virtual match-between-runs quantification in GlyPep-Quant improves site-specific glycan identification

Library-based virtual match-between-runs quantification in GlyPep-Quant improves site-specific glycan identification

Abstract Glycosylation changes are closely related to various diseases, including cancer. The quantitative analysis of site-specific glycans at proteomics scale remains challenging due to low glycopeptide spectra interpretation. Here, we present GlyPep-Quant, a tool for sensitive quantification and...

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Bibliographic Details
Main Authors: He Zhu, Zheng Fang, Lei Liu, Yan Wang, Hongqiang Qin, Yongzhan Nie, Mingming Dong, Mingliang Ye
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61673-6
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