Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series

Pruritus commonly occurs in patients with cholestatic liver diseases. Pruritus that is refractory to pharmacological treatment may be an indication for liver transplantation [1–3]. Pathogenesis of hepatic pruritus is still not fully understood. However, it is probably associated with the accumulatio...

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Main Authors: Magdalena Antoszewska, Piotr Spychalski, Gerda Elisabeth Villadsen, Niels Kristian Muff Aagaard
Format: Article
Language:English
Published: Termedia Publishing House 2021-09-01
Series:Gastroenterology Review
Online Access:https://www.termedia.pl/Treatment-of-intractable-pruritus-in-patients-with-r-ncholestasis-with-molecular-adsorbents-recirculating-r-nsystem-dialysis-a-case-series,41,45099,1,1.html
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author Magdalena Antoszewska
Piotr Spychalski
Gerda Elisabeth Villadsen
Niels Kristian Muff Aagaard
author_facet Magdalena Antoszewska
Piotr Spychalski
Gerda Elisabeth Villadsen
Niels Kristian Muff Aagaard
author_sort Magdalena Antoszewska
collection DOAJ
description Pruritus commonly occurs in patients with cholestatic liver diseases. Pruritus that is refractory to pharmacological treatment may be an indication for liver transplantation [1–3]. Pathogenesis of hepatic pruritus is still not fully understood. However, it is probably associated with the accumulation of pruritogens in plasma and other tissues as a result of cholestasis [4] (bile salts, bile acids, progesterone metabolites, lysophosphatidic acid, endogenous opioids [1]).
format Article
id doaj-art-1b48efd3e2524eab93daefdf40daf906
institution Kabale University
issn 1895-5770
1897-4317
language English
publishDate 2021-09-01
publisher Termedia Publishing House
record_format Article
series Gastroenterology Review
spelling doaj-art-1b48efd3e2524eab93daefdf40daf9062025-01-10T14:06:17ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172021-09-0116325425610.5114/pg.2021.10899245099Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case seriesMagdalena AntoszewskaPiotr SpychalskiGerda Elisabeth VilladsenNiels Kristian Muff AagaardPruritus commonly occurs in patients with cholestatic liver diseases. Pruritus that is refractory to pharmacological treatment may be an indication for liver transplantation [1–3]. Pathogenesis of hepatic pruritus is still not fully understood. However, it is probably associated with the accumulation of pruritogens in plasma and other tissues as a result of cholestasis [4] (bile salts, bile acids, progesterone metabolites, lysophosphatidic acid, endogenous opioids [1]).https://www.termedia.pl/Treatment-of-intractable-pruritus-in-patients-with-r-ncholestasis-with-molecular-adsorbents-recirculating-r-nsystem-dialysis-a-case-series,41,45099,1,1.html
spellingShingle Magdalena Antoszewska
Piotr Spychalski
Gerda Elisabeth Villadsen
Niels Kristian Muff Aagaard
Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
Gastroenterology Review
title Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
title_full Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
title_fullStr Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
title_full_unstemmed Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
title_short Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series
title_sort treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis a case series
url https://www.termedia.pl/Treatment-of-intractable-pruritus-in-patients-with-r-ncholestasis-with-molecular-adsorbents-recirculating-r-nsystem-dialysis-a-case-series,41,45099,1,1.html
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AT gerdaelisabethvilladsen treatmentofintractablepruritusinpatientswithcholestasiswithmolecularadsorbentsrecirculatingsystemdialysisacaseseries
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