Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions
Objective The objective of this study was to assess the efficacy of focused ultrasound ablation surgery (FUAS) in treating patients with adenomyosis and coexisting pelvic adhesions.Materials and methods A total of 396 patients diagnosed with adenomyosis and who underwent FUAS between January 2014 an...
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Taylor & Francis Group
2025-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2025.2461456 |
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| author | Jinfeng Lin Zhiyun Yang Lu Wang Zhibo Xiao Tao Tan Jinyun Chen |
| author_facet | Jinfeng Lin Zhiyun Yang Lu Wang Zhibo Xiao Tao Tan Jinyun Chen |
| author_sort | Jinfeng Lin |
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| description | Objective The objective of this study was to assess the efficacy of focused ultrasound ablation surgery (FUAS) in treating patients with adenomyosis and coexisting pelvic adhesions.Materials and methods A total of 396 patients diagnosed with adenomyosis and who underwent FUAS between January 2014 and December 2022 were enrolled. Pelvic adhesions were evaluated using magnetic resonance imaging (MRI), and the patients were categorized into either adhesive group or non-adhesive group. The aim was to investigate the comparative efficacy between the two groups.Results Among the 396 patients, pelvic adhesions were detected in 123 (31.06%) women. Compared to the non-adhesive group, patients in the adhesive group exhibited a higher preoperative dysmenorrhea score (7 vs. 6, p < 0.001), a lower short-term clinical success rate (74.80% vs. 84.62%, p = 0.025), and a higher long-term cumulative recurrence rate (log-rank p = 0.009). The adhesive group exhibited a high incidence of anal discomfort during the procedure compared to the non-adhesive group (18.70% vs. 7.69%, p = 0.002). Additionally, patients with severe adhesion demonstrated a lower ratio of non-perfused volume ratio (NPVR) (38.81% vs. 46.58%, p = 0.009). Multivariate binary logistic regression analysis revealed that pelvic adhesion independently increased the risk of dysmenorrhea (OR = 4.730, 95%CI: 2.026–11.044, p < 0.001), while severe pelvic adhesion was identified as an independent risk factor for NPVR (OR = 2.226, 95%CI: 1.181–4.196, p = 0.013).Conclusion The preoperative assessment of pelvic adhesions plays a crucial role in predicting intraoperative adverse events of FUAS in patients with adenomyosis, as well as determining both short-term and long-term efficacy, thereby providing valuable guidance for the development of comprehensive treatment. |
| format | Article |
| id | doaj-art-1b37c489d9464771a8fe0c0ce1310f10 |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
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| series | International Journal of Hyperthermia |
| spelling | doaj-art-1b37c489d9464771a8fe0c0ce1310f102025-08-20T03:48:23ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572025-12-0142110.1080/02656736.2025.2461456Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesionsJinfeng Lin0Zhiyun Yang1Lu Wang2Zhibo Xiao3Tao Tan4Jinyun Chen5State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaState Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaState Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaState Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaState Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaObjective The objective of this study was to assess the efficacy of focused ultrasound ablation surgery (FUAS) in treating patients with adenomyosis and coexisting pelvic adhesions.Materials and methods A total of 396 patients diagnosed with adenomyosis and who underwent FUAS between January 2014 and December 2022 were enrolled. Pelvic adhesions were evaluated using magnetic resonance imaging (MRI), and the patients were categorized into either adhesive group or non-adhesive group. The aim was to investigate the comparative efficacy between the two groups.Results Among the 396 patients, pelvic adhesions were detected in 123 (31.06%) women. Compared to the non-adhesive group, patients in the adhesive group exhibited a higher preoperative dysmenorrhea score (7 vs. 6, p < 0.001), a lower short-term clinical success rate (74.80% vs. 84.62%, p = 0.025), and a higher long-term cumulative recurrence rate (log-rank p = 0.009). The adhesive group exhibited a high incidence of anal discomfort during the procedure compared to the non-adhesive group (18.70% vs. 7.69%, p = 0.002). Additionally, patients with severe adhesion demonstrated a lower ratio of non-perfused volume ratio (NPVR) (38.81% vs. 46.58%, p = 0.009). Multivariate binary logistic regression analysis revealed that pelvic adhesion independently increased the risk of dysmenorrhea (OR = 4.730, 95%CI: 2.026–11.044, p < 0.001), while severe pelvic adhesion was identified as an independent risk factor for NPVR (OR = 2.226, 95%CI: 1.181–4.196, p = 0.013).Conclusion The preoperative assessment of pelvic adhesions plays a crucial role in predicting intraoperative adverse events of FUAS in patients with adenomyosis, as well as determining both short-term and long-term efficacy, thereby providing valuable guidance for the development of comprehensive treatment.https://www.tandfonline.com/doi/10.1080/02656736.2025.2461456Focused ultrasound ablation surgeryadenomyosispelvic adhesionsdysmenorrheatreatment efficacy |
| spellingShingle | Jinfeng Lin Zhiyun Yang Lu Wang Zhibo Xiao Tao Tan Jinyun Chen Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions International Journal of Hyperthermia Focused ultrasound ablation surgery adenomyosis pelvic adhesions dysmenorrhea treatment efficacy |
| title | Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| title_full | Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| title_fullStr | Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| title_full_unstemmed | Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| title_short | Efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| title_sort | efficacy of focused ultrasound ablation surgery in patients with adenomyosis and coexisting pelvic adhesions |
| topic | Focused ultrasound ablation surgery adenomyosis pelvic adhesions dysmenorrhea treatment efficacy |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2025.2461456 |
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