Effects of smail volumes of blood, isotonic and hypertonic saline administrations on haematological parometers and electrolytes in experimentally induced haemorrhagic shock in dogs
In this study, the effects of smail volumes of blood, isotonic and hypertonic saline administrations in dogs with haemorrhagic shock induced experimentally were investigated. For this purpose totally 20 dogs were usedas a material. The dogs were divided into 4 groups each of 5 dogs. the dogs were an...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=800 |
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| Summary: | In this study, the effects of smail volumes
of blood, isotonic and hypertonic saline administrations in
dogs with haemorrhagic shock induced experimentally
were investigated. For this purpose totally 20 dogs were
usedas a material. The dogs were divided into 4 groups
each of 5 dogs. the dogs were anesthetized with thiopenthal
sodium (30 mg/kg, iv), and then haemorrhagic
shock was performed experimentally. The mean artarial
pressura (MAP) was reduced to 40+5mmHg and maintained
at this /eve/ for 30 min (hypotensive period).<p>
At the end of the hypotensive period, the dogs of the
group I,II,III and IV were treated by bo/us injection of
5ml/kg of blood, isotonic, 3.5% and 7.5% NaCl, respectively.<p>
The blood samples for the determination of hemogram
were taken before the experiment, at the end of the
hypotensive period and after treatment at 30 th, 60th and
90th mins.<p>
Before the experiment, the mean values of RBC, in
group I,II,III and IV were found to be 5.37, 6.38, 5.58 and
6.23x10<sup>6</sup>/mm<sup>3</sup>, respectively. This values were fo und to
be 4.98, 6.00, 4,71 and 5.35x10<sup>6</sup>/mm<sup>3</sup>, at the end of the
hypotensive period, respectively. After the bo/us injection,
the RBC at 90th mins in group I,II,III and IV were determined
to be 4.97, 5.63, 4.35 and 4. 15x10<sup>6</sup>/mm<sup>3</sup>, respectively.<p>
Before the experiment, while the haemarocrit values
of group I,II,III and IV were determined to be 39.2, 47.2, 40. 7 and 43. 7 % respectively. The same va/ues were found to be 35.6, 42.3, 34.1 and 39.0 %, at the e nd of the
hypotensive period. The haematocrit values at 90th mins
in group /,ll, lll and IV were determined to be 34.4, 41.3,
30.9 and 28.5 %, respectively.<p>
Before the experiment, while the plasma sodium leve/
s in group I,II,III and IV were determined to be 134. 9,
137.9, 137.0 and 141.1 mEq/L, respectively. The same
values were found to be 133.5, 136.8, 133.6 and 135.7
mEq/L, at the en d of the hypotensive period, respectively. On the other hand, the plasma sodium values, at 90th
min s in group I,II,III and IV were determined to be 136. 6,
136.4, 136. B and 144.3 mEq/L, respectively.<p>
Before the experiment, the plasma potassium /eve/s in
group I,II,III and IV were determined to be 4.98, 5.27, 5.07
and 5.06 mEq/L, respectively. At the end of the hypotensive
period, the plasma potassium levels in the all
groups increased. At 90th mins these values in the all
groups decreased. |
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| ISSN: | 1309-6958 2146-1953 |