Dysregulation of adipocytokines via the hsa-miR-548ay-3p/PPARγ signaling pathway leads to cardiac fibrosis

Dysregulation of adipocytokines via the hsa-miR-548ay-3p/PPARγ signaling pathway leads to cardiac fibrosis

Abstract Cardiac fibrosis is a chief cause of atrial fibrillation (AF), yet its mechanism is not fully understood. Our previous study found that fibrosis-related adipocytokines were dysregulated in epicardial adipose tissue (EAT) from patients with AF. The present study explored the factors inducing...

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Bibliographic Details
Main Authors: Yubin Chen, Cheng Fang, Wei Liu, Kaibo Lei, Ping Hu, Can-e Tang, Lin Wang, Fanyan Luo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Atrial fibrillation
Cardiac fibrosis
Epicardial adipose tissue
miRNA
Adipocytokine
Online Access:https://doi.org/10.1038/s41598-025-11324-z
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https://doi.org/10.1038/s41598-025-11324-z

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