Advanced techniques and nanotechnologies for point-of-care testing
Hospitals and other healthcare facilities harbor a complex interplay of microbial pathogens. The correct understanding of pathogens distribution and evolution is therefore crucial for infections control and for the design of effective prevention strategies. In parallel, the integration of cutting-ed...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Nanotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnano.2024.1465429/full |
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| author | Valeria Secchi Valeria Secchi Alice Armanni Linda Barbieri Antonia Bruno Alessandro Colombo Sara Fumagalli Ekaterina A. Kukushkina Roberto Lorenzi Letizia Marchesi Hind Moukham Alberto Paleari Alessandra Ronchi Giulia Tomaino Farida Tripodi Miriam Colombo Miriam Colombo Laura Sironi Angelo Monguzzi Angelo Monguzzi |
| author_facet | Valeria Secchi Valeria Secchi Alice Armanni Linda Barbieri Antonia Bruno Alessandro Colombo Sara Fumagalli Ekaterina A. Kukushkina Roberto Lorenzi Letizia Marchesi Hind Moukham Alberto Paleari Alessandra Ronchi Giulia Tomaino Farida Tripodi Miriam Colombo Miriam Colombo Laura Sironi Angelo Monguzzi Angelo Monguzzi |
| author_sort | Valeria Secchi |
| collection | DOAJ |
| description | Hospitals and other healthcare facilities harbor a complex interplay of microbial pathogens. The correct understanding of pathogens distribution and evolution is therefore crucial for infections control and for the design of effective prevention strategies. In parallel, the integration of cutting-edge nanotechnologies for the early detection and monitoring of these specific target pathogens is considered the most effective approach to face nosocomial infections. In this context, point-of-care (POC) testing, also known as near-patient testing, is becoming increasingly important. In this review we provide a systematic insight into the recent scientific and technological advances in pathogen detection that explore advanced nanotechnologies to realize devices and nanobiosensors, with improved selectivity and sensitivity. In particular, we report on the most diffused and affordable nanotechnologies developed and still developing for POC testing, with the aim to increase the sensitivity, speed and accuracy of pathogens detection in different environments, from intensive care units to outside the laboratory and hospital settings. The text is sub-divided in several sections, each one focused on different type of nanomaterials and techniques actually employed. |
| format | Article |
| id | doaj-art-1ad9ac54423f4fe0bfabcdb38abc8509 |
| institution | Kabale University |
| issn | 2673-3013 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nanotechnology |
| spelling | doaj-art-1ad9ac54423f4fe0bfabcdb38abc85092025-01-15T06:10:32ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132025-01-01610.3389/fnano.2024.14654291465429Advanced techniques and nanotechnologies for point-of-care testingValeria Secchi0Valeria Secchi1Alice Armanni2Linda Barbieri3Antonia Bruno4Alessandro Colombo5Sara Fumagalli6Ekaterina A. Kukushkina7Roberto Lorenzi8Letizia Marchesi9Hind Moukham10Alberto Paleari11Alessandra Ronchi12Giulia Tomaino13Farida Tripodi14Miriam Colombo15Miriam Colombo16Laura Sironi17Angelo Monguzzi18Angelo Monguzzi19Department of Materials Science, University of Milano-Bicocca, Milano, ItalyNANOMIB, Center for Biomedical Nanomedicine, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Materials Science, University of Milano-Bicocca, Milano, ItalyDepartment of Materials Science, University of Milano-Bicocca, Milano, ItalyDepartment of Physics, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Materials Science, University of Milano-Bicocca, Milano, ItalyDepartment of Materials Science, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyNANOMIB, Center for Biomedical Nanomedicine, University of Milano-Bicocca, Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, ItalyDepartment of Physics, University of Milano-Bicocca, Milano, ItalyDepartment of Materials Science, University of Milano-Bicocca, Milano, ItalyNANOMIB, Center for Biomedical Nanomedicine, University of Milano-Bicocca, Milano, ItalyHospitals and other healthcare facilities harbor a complex interplay of microbial pathogens. The correct understanding of pathogens distribution and evolution is therefore crucial for infections control and for the design of effective prevention strategies. In parallel, the integration of cutting-edge nanotechnologies for the early detection and monitoring of these specific target pathogens is considered the most effective approach to face nosocomial infections. In this context, point-of-care (POC) testing, also known as near-patient testing, is becoming increasingly important. In this review we provide a systematic insight into the recent scientific and technological advances in pathogen detection that explore advanced nanotechnologies to realize devices and nanobiosensors, with improved selectivity and sensitivity. In particular, we report on the most diffused and affordable nanotechnologies developed and still developing for POC testing, with the aim to increase the sensitivity, speed and accuracy of pathogens detection in different environments, from intensive care units to outside the laboratory and hospital settings. The text is sub-divided in several sections, each one focused on different type of nanomaterials and techniques actually employed.https://www.frontiersin.org/articles/10.3389/fnano.2024.1465429/fullnanotechnologynanobiosensorspathogenspoint-of-carepathogens detection |
| spellingShingle | Valeria Secchi Valeria Secchi Alice Armanni Linda Barbieri Antonia Bruno Alessandro Colombo Sara Fumagalli Ekaterina A. Kukushkina Roberto Lorenzi Letizia Marchesi Hind Moukham Alberto Paleari Alessandra Ronchi Giulia Tomaino Farida Tripodi Miriam Colombo Miriam Colombo Laura Sironi Angelo Monguzzi Angelo Monguzzi Advanced techniques and nanotechnologies for point-of-care testing Frontiers in Nanotechnology nanotechnology nanobiosensors pathogens point-of-care pathogens detection |
| title | Advanced techniques and nanotechnologies for point-of-care testing |
| title_full | Advanced techniques and nanotechnologies for point-of-care testing |
| title_fullStr | Advanced techniques and nanotechnologies for point-of-care testing |
| title_full_unstemmed | Advanced techniques and nanotechnologies for point-of-care testing |
| title_short | Advanced techniques and nanotechnologies for point-of-care testing |
| title_sort | advanced techniques and nanotechnologies for point of care testing |
| topic | nanotechnology nanobiosensors pathogens point-of-care pathogens detection |
| url | https://www.frontiersin.org/articles/10.3389/fnano.2024.1465429/full |
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