The distrubution of immune system cells in bursa of fabricius of partridge (alectoris chukar)
<b> Aim:</b> The bursa of Fabricius is a primary lymphoid organ restricted to birds that is responsible for the proliferation and differentiation of B lymphocyte precursors within its follicular structure. In the process of creating a functional B lymphocyte, the cells acquire the necess...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Selcuk University Press
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Series: | Eurasian Journal of Veterinary Sciences |
Subjects: | |
Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1157 |
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Summary: | <b> Aim:</b> The bursa of Fabricius is a primary lymphoid organ
restricted to birds that is responsible for the proliferation
and differentiation of B lymphocyte precursors within
its follicular structure. In the process of creating a functional
B lymphocyte, the cells acquire the necessary receptor
property to recognize the antigen, major histocompatibility
complex and adhesion molecules in this organ. The purpose
of this study is to determine the localization and distribution
of CD8, CD68, MHC-I and II-positive cells in bursa of Fabricius
of partridge.<p>
<b> Materials and Methods:</b> In this study, some immune cells
localization in bursa of Fabricius of 10 adult chukar partridge
(5 male and 5 female) were examined on the level of light
microscope by using immunohistochemical methods.<p>
<b> Results:</b> It was revealed that in general CD8, CD68, MHC-I
and II-positive cells were localized in lamina propria and cortex
and medulla of lymph follicles. In contrast, no immunoreactivity
was observed in the muscle layer.<p>
<b> Conclusion:</b> The expression of these factors playing a role
in immune response is thought to provide contribution for
immunological studies in avian species. |
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ISSN: | 1309-6958 2146-1953 |