SARS-CoV-2 membrane protein induces neurodegeneration via affecting Golgi-mitochondria interaction

SARS-CoV-2 membrane protein induces neurodegeneration via affecting Golgi-mitochondria interaction

Abstract Background Neurological complications are a significant concern of Coronavirus Disease 2019 (COVID-19). However, the pathogenic mechanism of neurological symptoms associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is poorly understood. Methods We used Dro...

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Main Authors: Fang Wang, Hailong Han, Caifang Wang, Jingfei Wang, Yanni Peng, Ye Chen, Yaohui He, Zhouyang Deng, Fang Li, Yikang Rong, Danling Wang, Wen Liu, Hualan Chen, Zhuohua Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Translational Neurodegeneration
Subjects:
COVID-19
Alzheimer’s disease
Mitochondria
PI4KIIIβ
Brain
Online Access:https://doi.org/10.1186/s40035-024-00458-1
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