In Vivo Quantitative Measurement of Arthritis Activity Based on Hydrophobically Modified Glycol Chitosan in Inflammatory Arthritis: More Active than Passive Accumulation

In Vivo Quantitative Measurement of Arthritis Activity Based on Hydrophobically Modified Glycol Chitosan in Inflammatory Arthritis: More Active than Passive Accumulation

We demonstrated that arthritis could be visualized noninvasively using hydrophobically modified glycol chitosan nanoparticles labeled with Cy5.5 (HGC-Cy5.5) and an optical imaging system. Activated macrophages expressing Mac-1 molecules effectively phagocytosed HGC-Cy5.5, which formed spherical nano...

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Main Authors: Kyeong Soon Park, Jin Hee Kang, Keum Hee Sa, Hee Beom Koo, Hyun Jung Cho, Eon Jeong Nam, In Chan Youn, Kwang Meyung Kim, In San Kim, Ick Chan Kwon, Kui Won Choi, Young Mo Kang
Format: Article
Language:English
Published: SAGE Publishing 2012-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00056
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