Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes

Due to the active usage of antibacterial drugs in animal husbandry, antibiotic residues and antibiotic-resistance genes enter the soil when it is fertilized with manure and compost. In this work, we estimated the spread of antibiotic-resistance genes in the soil when it was fertilized with composts...

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Main Authors: N.V. Danilova, P.A. Kuryntseva, M.Sh. Tagirov, P.Yu. Galitskaya, S.Yu. Selivanovskaya
Format: Article
Language:English
Published: Kazan Federal University 2019-09-01
Series:Учёные записки Казанского университета: Серия Естественные науки
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Online Access:https://kpfu.ru/uz-eng-ns-2019-3-4.html
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author N.V. Danilova
P.A. Kuryntseva
M.Sh. Tagirov
P.Yu. Galitskaya
S.Yu. Selivanovskaya
author_facet N.V. Danilova
P.A. Kuryntseva
M.Sh. Tagirov
P.Yu. Galitskaya
S.Yu. Selivanovskaya
author_sort N.V. Danilova
collection DOAJ
description Due to the active usage of antibacterial drugs in animal husbandry, antibiotic residues and antibiotic-resistance genes enter the soil when it is fertilized with manure and compost. In this work, we estimated the spread of antibiotic-resistance genes in the soil when it was fertilized with composts containing oxytetracycline (OTC) and tetracycline-resistance genes. The following mixtures were studied for 35 days: the soil with “clean” compost, the soil with compost and 300 mg kg–1 OTC, the soil with compost and antibiotic-resistance genes. In the soil treated with composts, the number of bacteria and fungi increased, with the greatest changes in the number of bacteria observed for the soil with compost containing OTC. The addition of compost with the antibiotic and the resistance genes tet(M) and tet(X) to the soil led to the formation of antibiotic resistance in soil microorganisms with the highest number of gene copies for 5–7 days: an average of 3.31?106 and 7.77?106 copies g-1, respectively. Both genes, tet(M) and tet(X), but in smaller numbers, were detected in the soil with “clean” compost on days 14–21, respectively.
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institution Kabale University
issn 2542-064X
2500-218X
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publishDate 2019-09-01
publisher Kazan Federal University
record_format Article
series Учёные записки Казанского университета: Серия Естественные науки
spelling doaj-art-19bd004440424b4f9fbe01d8b7aefbb22025-01-02T11:36:19ZengKazan Federal UniversityУчёные записки Казанского университета: Серия Естественные науки2542-064X2500-218X2019-09-01161339540710.26907/2542-064X.2019.3.395-407Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genesN.V. Danilova0P.A. Kuryntseva1M.Sh. Tagirov2P.Yu. Galitskaya3S.Yu. Selivanovskaya4Kazan Federal University, Kazan, 420008 RussiaKazan Federal University, Kazan, 420008 RussiaTatar Scientific Research Institute of Agriculture, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan, 420059 RussiaKazan Federal University, Kazan, 420008 RussiaKazan Federal University, Kazan, 420008 RussiaDue to the active usage of antibacterial drugs in animal husbandry, antibiotic residues and antibiotic-resistance genes enter the soil when it is fertilized with manure and compost. In this work, we estimated the spread of antibiotic-resistance genes in the soil when it was fertilized with composts containing oxytetracycline (OTC) and tetracycline-resistance genes. The following mixtures were studied for 35 days: the soil with “clean” compost, the soil with compost and 300 mg kg–1 OTC, the soil with compost and antibiotic-resistance genes. In the soil treated with composts, the number of bacteria and fungi increased, with the greatest changes in the number of bacteria observed for the soil with compost containing OTC. The addition of compost with the antibiotic and the resistance genes tet(M) and tet(X) to the soil led to the formation of antibiotic resistance in soil microorganisms with the highest number of gene copies for 5–7 days: an average of 3.31?106 and 7.77?106 copies g-1, respectively. Both genes, tet(M) and tet(X), but in smaller numbers, were detected in the soil with “clean” compost on days 14–21, respectively.https://kpfu.ru/uz-eng-ns-2019-3-4.htmlantibioticsoxytetracyclineantibiotic resistanceantibiotic-resistance genescompostreal-time pcr
spellingShingle N.V. Danilova
P.A. Kuryntseva
M.Sh. Tagirov
P.Yu. Galitskaya
S.Yu. Selivanovskaya
Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
Учёные записки Казанского университета: Серия Естественные науки
antibiotics
oxytetracycline
antibiotic resistance
antibiotic-resistance genes
compost
real-time pcr
title Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
title_full Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
title_fullStr Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
title_full_unstemmed Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
title_short Spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic-resistant genes
title_sort spreading of antibiotic resistance as a result of soil fertilization by manure composts containing oxytetracycline and antibiotic resistant genes
topic antibiotics
oxytetracycline
antibiotic resistance
antibiotic-resistance genes
compost
real-time pcr
url https://kpfu.ru/uz-eng-ns-2019-3-4.html
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