Prognostic Features and Potential for Immune Therapy in Metastatic Mismatch Repair‐Deficient Colorectal Cancer: A Retrospective Analysis of a Large Consecutive Population‐Based Patient Series

Prognostic Features and Potential for Immune Therapy in Metastatic Mismatch Repair‐Deficient Colorectal Cancer: A Retrospective Analysis of a Large Consecutive Population‐Based Patient Series

ABSTRACT Background Immune checkpoint inhibition therapies have provided remarkable results in numerous metastatic cancers, including mismatch repair–deficient (dMMR) colorectal cancer (CRC). To evaluate the potential for PD‐1 blockade therapy in a large population‐based cohort, we analyzed the tumo...

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Main Authors: Erkki‐Ville Wirta, Hanna Elomaa, Jukka‐Pekka Mecklin, Toni T. Seppälä, Marja Hyöty, Jan Böhm, Maarit Ahtiainen, Juha P. Väyrynen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Cancer Medicine
Online Access:https://doi.org/10.1002/cam4.70555
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