Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

ABSTRACT Metabolic engineering of Saccharomyces cerevisiae has enabled xylose‐fermenting yeast strains. However, the bioavailability dilemma of xylose has become the core bottleneck restricting the economy of lignocellulose. This study investigates the overexpression of the transketolase gene (TKL1)...

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Bibliographic Details
Main Authors: Si Xu, Wanli Cheng, Huanan Li, Jiashu Liu, Kexin Chen, Zhengbing Jiang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:GCB Bioenergy
Subjects:
conversion of sugar alcohols
glucose/xylose co‐utilization
Saccharomyces cerevisiae
transketolase
Online Access:https://doi.org/10.1111/gcbb.70053
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