Central Retinal Artery Occlusion Associated with Sildenafil Overdose

Background. To report a patient with central retinal artery occlusion (CRAO) associated with sildenafil overdose. Case Presentation. A forty-two-year-old male presented three hours after sudden painless visual loss in the right eye. BCVA was counting finger in two meters, and relative afferent pupil...

Full description

Saved in:
Bibliographic Details
Main Authors: Mojtaba Abrishami, Seyedeh Maryam Hosseini, Hamid Mohseni, Majid Razavi, Amir Ghaffarian Mashhadi Nejad, Mohammad Baghi Yazdi, Ghodsieh Zamani
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/2006271
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849304373453127680
author Mojtaba Abrishami
Seyedeh Maryam Hosseini
Hamid Mohseni
Majid Razavi
Amir Ghaffarian Mashhadi Nejad
Mohammad Baghi Yazdi
Ghodsieh Zamani
author_facet Mojtaba Abrishami
Seyedeh Maryam Hosseini
Hamid Mohseni
Majid Razavi
Amir Ghaffarian Mashhadi Nejad
Mohammad Baghi Yazdi
Ghodsieh Zamani
author_sort Mojtaba Abrishami
collection DOAJ
description Background. To report a patient with central retinal artery occlusion (CRAO) associated with sildenafil overdose. Case Presentation. A forty-two-year-old male presented three hours after sudden painless visual loss in the right eye. BCVA was counting finger in two meters, and relative afferent pupillary defect was positive. Fundus examination revealed retinal whiteness except in a limited area of papillomacular bundle and cherry red spot. He consumed two 100 mg film-coated sildenafil tablet (Vizarsin, Krka, d.d., Novo mesto, Slovenia) twelve hours apart, and the last one was six hours before visual loss. He was diagnosed with CRAO with cilioretinal artery sparing. Although we did not find any emboli, anterior chamber paracentesis was done. Four weeks later, BCVA improved to 20/80, with resolving of retinal edema. Cardiovascular, carotid arteries, and neurologic evaluations were negative for any predisposing factor. Conclusion. CRAO is a vision threatening condition that might be associated with the overdose of sildenafil.
format Article
id doaj-art-19230e1c16a34c6f86b3c63bff35d6d1
institution Kabale University
issn 2090-6722
2090-6730
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Ophthalmological Medicine
spelling doaj-art-19230e1c16a34c6f86b3c63bff35d6d12025-08-20T03:55:45ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/20062712006271Central Retinal Artery Occlusion Associated with Sildenafil OverdoseMojtaba Abrishami0Seyedeh Maryam Hosseini1Hamid Mohseni2Majid Razavi3Amir Ghaffarian Mashhadi Nejad4Mohammad Baghi Yazdi5Ghodsieh Zamani6Eye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranBackground. To report a patient with central retinal artery occlusion (CRAO) associated with sildenafil overdose. Case Presentation. A forty-two-year-old male presented three hours after sudden painless visual loss in the right eye. BCVA was counting finger in two meters, and relative afferent pupillary defect was positive. Fundus examination revealed retinal whiteness except in a limited area of papillomacular bundle and cherry red spot. He consumed two 100 mg film-coated sildenafil tablet (Vizarsin, Krka, d.d., Novo mesto, Slovenia) twelve hours apart, and the last one was six hours before visual loss. He was diagnosed with CRAO with cilioretinal artery sparing. Although we did not find any emboli, anterior chamber paracentesis was done. Four weeks later, BCVA improved to 20/80, with resolving of retinal edema. Cardiovascular, carotid arteries, and neurologic evaluations were negative for any predisposing factor. Conclusion. CRAO is a vision threatening condition that might be associated with the overdose of sildenafil.http://dx.doi.org/10.1155/2021/2006271
spellingShingle Mojtaba Abrishami
Seyedeh Maryam Hosseini
Hamid Mohseni
Majid Razavi
Amir Ghaffarian Mashhadi Nejad
Mohammad Baghi Yazdi
Ghodsieh Zamani
Central Retinal Artery Occlusion Associated with Sildenafil Overdose
Case Reports in Ophthalmological Medicine
title Central Retinal Artery Occlusion Associated with Sildenafil Overdose
title_full Central Retinal Artery Occlusion Associated with Sildenafil Overdose
title_fullStr Central Retinal Artery Occlusion Associated with Sildenafil Overdose
title_full_unstemmed Central Retinal Artery Occlusion Associated with Sildenafil Overdose
title_short Central Retinal Artery Occlusion Associated with Sildenafil Overdose
title_sort central retinal artery occlusion associated with sildenafil overdose
url http://dx.doi.org/10.1155/2021/2006271
work_keys_str_mv AT mojtabaabrishami centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT seyedehmaryamhosseini centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT hamidmohseni centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT majidrazavi centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT amirghaffarianmashhadinejad centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT mohammadbaghiyazdi centralretinalarteryocclusionassociatedwithsildenafiloverdose
AT ghodsiehzamani centralretinalarteryocclusionassociatedwithsildenafiloverdose