Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease

Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease

BackgroundGynura procumbens (Lour.) Merr. is a plant used in traditional Chinese medicine that reduces hepatotoxicity, relieves kidney discomfort, and has anti-inflammatory and antioxidant properties. MethodsWe aimed to explore the mechanisms underlying the therapeutic effects of an ethanol extract...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ting-Ting Li, Li-Ying Wen, Sha-Sha Meng, Yu-Sang Li, He-Bin Tang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	chronic kidney disease renal anemia ethanol extract from Gynura procumbens stems chlorogenic acid trans-p-coumaric acid
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1476735/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process
by: M. Jeevitha, et al.
Published: (2024-12-01)

Anti-Inflammatory Activity and Free Radical Scavenging Activity of Tridax Procumbens Leaves-Based Chitosan Gel
by: R. Nandita, et al.
Published: (2024-12-01)

Ultrasonication-assisted lipase-catalyzed esterification of chlorogenic acid: A comparative study using fatty alcohol and acids in solvent and solvent-free conditions
by: Chia-Hung Kuo, et al.
Published: (2025-02-01)

ρ-Coumaric acid-zinc oxide nanoparticles improve post-thaw quality of goat spermatozoa and developmental competence of fertilized oocytes in vitro
by: Bahareh Akhtarshenas, et al.
Published: (2024-12-01)

Akkermansia muciniphila-directed polyphenol chlorogenic acid intervention for obesity in mice
by: Xiaoxiang Gao, et al.
Published: (2024-01-01)

The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia
by: Kai Shen, et al.
Published: (2025-02-01)

Minimal Inhibitory Concentration Assay of Tridax procumbens Stem Extract-Based Chitosan Gel against Pseudomonas aeruginosa
by: Sachin Aditya, et al.
Published: (2024-12-01)

Cross-protective effect of acid adaptation on ethanol tolerance in Salmonella Enteritidis
by: Shoukui He, et al.
Published: (2023-07-01)

Antiaging properties of chlorogenic acid through protein and gene biomarkers in human skin fibroblast cells as photoaging model
by: Ermi Girsang, et al.
Published: (2024-12-01)

Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas
by: N.B. Maulydia, et al.
Published: (2024-01-01)

Profiling Rosmarinic Acid and Sinensetin Content of Orthosiphon aristatus. from Three Different Locations with Variety Ethanol Concentration
by: Novia Putri Ramadhani, et al.
Published: (2024-08-01)

DFT and molecular docking analyses of the effects of solvent polarity and temperature on the structural, electronic, and thermodynamic properties of p-coumaric acid: Insights for anti-cancer applications
by: Umer Sherefedin, et al.
Published: (2025-01-01)

A Comparative Phytochemical Investigation of the Greek Members of the Genus <i>Helichrysum</i> Mill., with Emphasis on the Local Endemic <i>Helichrysum amorginum</i> Boiss and Orph
by: Iordanis Samanidis, et al.
Published: (2025-01-01)

Cinnamic Acid Compounds (<i>p</i>-Coumaric, Ferulic, and <i>p</i>-Methoxycinnamic Acid) as Effective Antibacterial Agents Against Colistin-Resistant <i>Acinetobacter baumannii</i>
by: Alaaddin Korkut, et al.
Published: (2025-01-01)

Efficacy of Chlorogenic Acid in Treating Tripterygium Glycoside-Induced Asthenozoospermia in Rats and Its Possible Mechanisms
by: Long Chen, et al.
Published: (2025-01-01)

Prognostic impact of moderate to severe anemia associated with renal dysfunction in patients with heart failure
by: Eri Noda, et al.
Published: (2025-01-01)

Effects of Endurance Training and Chlorogenic Acid on Oxidative and Nitrosative Stress Markers in Prediabetic Male Mice
by: Sahar Ghasemi Pour, et al.
Published: (2025-01-01)

Efficacy of Intravenous Versus Oral Administration of Levocarnitine in Maintenance Hemodialysis Patients: A Randomized Controlled Trial Investigating Therapeutic Approaches to Renal Anemia
by: Sadia Rehman, et al.
Published: (2025-01-01)

Chlorogenic acid alleviates cadmium-induced neuronal injury in chicken cerebral cortex by inhibiting incomplete autophagy mediated by AMPK-ULK1 pathway
by: Li Wang, et al.
Published: (2025-01-01)

Effect of eicosapentaenoic acid on innate immune responses in Atlantic salmon cells infected with infectious salmon anemia virus
by: Ingrid Holmlund, et al.
Published: (2025-01-01)

Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens
by: Haitong Zhao, et al.
Published: (2025-12-01)

Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
by: Agnieszka Zielińska, et al.
Published: (2020-12-01)

Chlorogenic acid complex (CGA7), standardized extract from green coffee beans exerts anticancer effects against cultured human colon cancer HCT-116 cells
by: K. Gouthamchandra, et al.
Published: (2017-09-01)

Determination of Trans-Fatty Acid Levels in Selected Syrian Food Products
by: Radwan Badr Al-Deen, et al.
Published: (2025-01-01)

Family-centered Health Education Intervention for Improving Iron−folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study
by: Gyanendra Singh, et al.
Published: (2024-12-01)

Effect of Premna pubescens Ethanol Extract on Erythrocyte Count and Kidney Histology in Rattus norvegicus L
by: Srinatalia Silaen
Published: (2025-01-01)

Functional Properties of Protein Isolate and Acid Soluble Protein-Rich Ingredient Co-Produced from Ethanol-Treated Industrial Rapeseed Meal
by: Hristo Kalaydzhiev, et al.
Published: (2019-03-01)

Association of iron deficiency with kidney outcome and all-cause mortality in chronic kidney disease patients without anemia
by: Hongxue Yu, et al.
Published: (2025-01-01)

Response mechanism of ethanol-tolerant Saccharomyces cerevisiae strain ES-42 to increased ethanol during continuous ethanol fermentation
by: Xue-Xue Ji, et al.
Published: (2025-01-01)

Therapy of resistant hypertension in patients with chronic kidney disease complications of anemia in hemodialysis: a case report
by: Yenry Sumarlim, et al.
Published: (2023-11-01)

Chlorogenic Acid and Biohanin A from Trifolium pratense L. Callus Culture Extract: Functional Activity In Vivo
by: Irina S. Milentyeva, et al.
Published: (2023-12-01)

Ethanol Production Yield from Cassava Mill Effluent using Starch Hydrolyzing Bacterium (Bacillus species) and Glucose Fermenting Yeast (Saccharomyces species)
by: L. P. Peekate, et al.
Published: (2025-02-01)

ANEMIA EN EL EMBARAZO
by: Enrique Guevara Ríos, et al.
Published: (2025-01-01)

Effect of ethanol concentration on the catalytic performance of WO3/MCF-Si and WO3/SBA-15 catalysts toward ethanol dehydration to ethylene
by: Pantita Trongjitraksa, et al.
Published: (2025-01-01)

Trans fatty acids and saturated fatty acids in margarines and spreads in Kazakhstan: Study period 2015–2021
by: Kainaubek Toshtay, et al.
Published: (2025-01-01)

Phytochemical analysis and anti-aging efficacy of two Egyptian sweet potato cultivars in a d-galactose-induced skin aging model
by: Rehab M. Elgabry, et al.
Published: (2025-01-01)

Hybrid Gel as a Substitute for Hard Fats in Confectionery
by: Vasilissa S. Kutsenkova, et al.
Published: (2023-03-01)

Evaluation of Sustainability of Brazilian Ethanol Production: A model in System Dynamics
by: Arnoldo Jose de Hoyos Guevara, et al.
Published: (2017-01-01)

Therapeutic effects of chlorogenic acid on allergic rhinitis through TLR4/MAPK/NF-κB pathway modulation
by: Xiaoyan Xu, et al.
Published: (2024-12-01)

THE ROLE OF ERYTHROPOIETIN IN TREATMENT OF ANEMIA IN CANCER PATIENTS
by: P. G. Berezin, et al.
Published: (2017-06-01)