Conotoxin kM-RIIIJ reveals interplay between Kv1-channels and persistent sodium currents in proprioceptive DRG neurons

Conotoxin kM-RIIIJ reveals interplay between Kv1-channels and persistent sodium currents in proprioceptive DRG neurons

Abstract Voltage-gated potassium channels (VGKCs) comprise the largest and most complex families of ion channels. Approximately 70 genes encode VGKC alpha subunits, which assemble into functional tetrameric channel complexes. These subunits can also combine to form heteromeric channels, significantl...

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Main Authors: Shrinivasan Raghuraman, Jackson Carter, Markel Walter, Manju Karthikeyan, Kevin Chase, Matías L. Giglio, Mario Giacobassi, Russell W. Teichert, Heinrich Terlau, Baldomero M. Olivera
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82165-5
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https://doi.org/10.1038/s41598-024-82165-5

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