Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

Small cell carcinoma of the esophagus (SCCE) is a rare and aggressively progressing malignancy that presents considerable clinical challenges.Although chemotherapy can effectively manage symptoms during the earlystages of SCCE, its long-term effectiveness is notably limited, with theunderlying mecha...

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Bibliographic Details
Main Authors: Qinkai Zhang, Ziyu Gao, Ru Qiu, Jizhao Cao, Chunxiao Zhang, Wei Qin, Meiling Yang, Xinyue Wang, Ciqiu Yang, Jie Li, Dongyang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Genetics
Subjects:
small cell carcinoma of the esophagus
single-cell RNA sequencing
chemotherapy
tumor microenvironment
cell plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1477705/full
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