Mechanisms underlying the involvement of peritoneal macrophages in the pathogenesis and novel therapeutic strategies for dialysis-induced peritoneal fibrosis

Mechanisms underlying the involvement of peritoneal macrophages in the pathogenesis and novel therapeutic strategies for dialysis-induced peritoneal fibrosis

Long-term exposure of the peritoneum to peritoneal dialysate results in pathophysiological changes in the anatomical organization of the peritoneum and progressive development of peritoneal fibrosis. This leads to a decline in peritoneal function and ultrafiltration failure, ultimately necessitating...

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Bibliographic Details
Main Authors: Yangwei Wang, Yixian Zhang, Mingqi Ma, Xiaohua Zhuang, Yue Lu, Lining Miao, Xuehong Lu, Yingchun Cui, Wenpeng Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
peritoneal dialysis
peritoneal fibrosis
macrophage
polarization
therapeutic strategies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1507265/full
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