Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer’s disease

Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer’s disease

Neuroinflammation plays an important role in the pathophysiology of Alzheimer’s disease. The cannabinoid type 2 receptor (CB2R) is an emerging target for neuroinflammation and therapeutics of Alzheimer’s disease. Here, we aim to assess the alterations in brain CB2R levels and evaluate novel CB2R ima...

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Bibliographic Details
Main Authors:	Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Achi Haider, Linjing Mu, Jan Klohs, Simon M. Ametamey, Ruiqing Ni
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Aging Neuroscience
Subjects:	Alzheimer’s disease positron emission tomography astrocyte microglia cannabinoid type 2 receptor (CB2R) neuroinflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.1018610/full
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