Mitochondrial inhibitors reveal roles of specific respiratory chain complexes in CRY-dependent degradation of TIM
Abstract Drosophila Cryptochrome (CRY) is an essential photoreceptor that mediates the resetting of the circadian clock by light. in vitro studies demonstrated a critical role of redox cycling of the FAD cofactor for CRY activation by light. However, it is unknown if CRY responds to cellular redox e...
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| Main Authors: | Xiangzhong Zheng, Dechun Chen, Brian Zoltowski, Amita Sehgal |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-77692-0 |
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