Mitochondrial inhibitors reveal roles of specific respiratory chain complexes in CRY-dependent degradation of TIM

Abstract Drosophila Cryptochrome (CRY) is an essential photoreceptor that mediates the resetting of the circadian clock by light. in vitro studies demonstrated a critical role of redox cycling of the FAD cofactor for CRY activation by light. However, it is unknown if CRY responds to cellular redox e...

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Bibliographic Details
Main Authors: Xiangzhong Zheng, Dechun Chen, Brian Zoltowski, Amita Sehgal
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-77692-0
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