Integrating traditional biomarkers and emerging predictors to assess neoadjuvant chemotherapy efficacy in breast cancer: a multifactorial analysis of Ki-67, CDK4, EGFR, TILs and ctDNA

Integrating traditional biomarkers and emerging predictors to assess neoadjuvant chemotherapy efficacy in breast cancer: a multifactorial analysis of Ki-67, CDK4, EGFR, TILs and ctDNA

Abstract Objective This study aimed to analyse the correlation between the expression of cell proliferation-associated antigen (Ki-67), cell cycle protein-dependent kinase 4 (CDK4), epidermal growth factor receptor (EGFR), tumour-infiltrating lymphocytes (TILs) and circulating tumour DNA (ctDNA) wit...

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Bibliographic Details
Main Authors: Tianzhao Du, Ye Yuan, Shulan Sun, Zhichao Gao, Xiaoshuai Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Women's Health
Subjects:
Ki-67
CDK4
EGFR
NACT
Breast cancer subtypes
Online Access:https://doi.org/10.1186/s12905-024-03486-1
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