Early management of adult sepsis and septic shock: Korean clinical practice guidelines
Background Despite recent advances and global improvements in sepsis recognition and supportive care, mortality rates remain high, and adherence to sepsis bundle components in Korea is low. To address this, the Korean Sepsis Alliance, affiliated with the Korean Society of Critical Care Medicine, dev...
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| Format: | Article |
| Language: | English |
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Korean Society of Critical Care Medicine
2024-11-01
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| Series: | Acute and Critical Care |
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| Online Access: | http://www.accjournal.org/upload/pdf/acc-2024-00920.pdf |
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| author | Chul Park Nam Su Ku Dae Won Park Joo Hyun Park Tae Sun Ha Do Wan Kim So Young Park Youjin Chang Kwang Wook Jo Moon Seong Baek Yijun Seo Tae Gun Shin Gina Yu Jongmin Lee Yong Jun Choi Ji Young Jang Yun Tae Jung Inseok Jeong Hwa Jin Cho Ala Woo Sua Kim Dae-Hwan Bae Sung Wook Kang Sun Hyo Park Gee Young Suh Sunghoon Park |
| author_facet | Chul Park Nam Su Ku Dae Won Park Joo Hyun Park Tae Sun Ha Do Wan Kim So Young Park Youjin Chang Kwang Wook Jo Moon Seong Baek Yijun Seo Tae Gun Shin Gina Yu Jongmin Lee Yong Jun Choi Ji Young Jang Yun Tae Jung Inseok Jeong Hwa Jin Cho Ala Woo Sua Kim Dae-Hwan Bae Sung Wook Kang Sun Hyo Park Gee Young Suh Sunghoon Park |
| author_sort | Chul Park |
| collection | DOAJ |
| description | Background Despite recent advances and global improvements in sepsis recognition and supportive care, mortality rates remain high, and adherence to sepsis bundle components in Korea is low. To address this, the Korean Sepsis Alliance, affiliated with the Korean Society of Critical Care Medicine, developed the first sepsis treatment guidelines for Korea based on a comprehensive systematic review and meta-analysis. Methods A de novo method was used to develop the guidelines. Methodologies included determining key questions, conducting a literature search and selection, assessing the risk of bias, synthesizing evidence, and developing recommendations. The certainty of evidence and the strength of recommendations were determined using the Grading of Recommendations, Assessment, Development, and Evaluations approach. Draft recommendations underwent internal and external review processes and public hearings. The development of these guidelines was supported by a research grant from the Korean Disease Control and Prevention Agency. Results In these guidelines, we focused on early treatments for adult patients with sepsis and septic shock. Through the guideline development process, 12 key questions and their respective recommendations were formulated. These include lactate measurement, fluid therapies, target blood pressure, antibiotic administration, use of vasopressors and dobutamine, extracorporeal membrane oxygenation, and echocardiography. Conclusions These guidelines aim to support medical professionals in making appropriate decisions about treating adult sepsis and septic shock. We hope these guidelines will increase awareness of sepsis and reduce its mortality rate. |
| format | Article |
| id | doaj-art-185e66e27d4c41f9bc48b56f12bcb4a3 |
| institution | DOAJ |
| issn | 2586-6052 2586-6060 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Korean Society of Critical Care Medicine |
| record_format | Article |
| series | Acute and Critical Care |
| spelling | doaj-art-185e66e27d4c41f9bc48b56f12bcb4a32025-08-20T03:02:18ZengKorean Society of Critical Care MedicineAcute and Critical Care2586-60522586-60602024-11-0139444547210.4266/acc.2024.009201561Early management of adult sepsis and septic shock: Korean clinical practice guidelinesChul Park0Nam Su Ku1Dae Won Park2Joo Hyun Park3Tae Sun Ha4Do Wan Kim5So Young Park6Youjin Chang7Kwang Wook Jo8Moon Seong Baek9Yijun Seo10Tae Gun Shin11Gina Yu12Jongmin Lee13Yong Jun Choi14Ji Young Jang15Yun Tae Jung16Inseok Jeong17Hwa Jin Cho18Ala Woo19Sua Kim20Dae-Hwan Bae21Sung Wook Kang22Sun Hyo Park23Gee Young Suh24Sunghoon Park25 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea Division of Infective Diseases, Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea Division of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Respiratory Medicine, Department of Internal Medicine, Seoul Metropolitan Seonam Hospital, Seoul, Korea Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital and Medical School, Gwangju, Korea Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Sanggye Paik Hospital, College of Medicine, Inje University Seoul, Korea Department of Neurosurgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Emergency Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Department of Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea Department of Surgery, Gangneung Asan Hospital, Gangneung, Korea Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital and Medical School, Gwangju, Korea Department of Pediatrics, Chonnam National University Children's Hospital, Chonnam National University Medical School, Gwangju, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Department of Critical Care Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea Department of Critical Care Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, KoreaBackground Despite recent advances and global improvements in sepsis recognition and supportive care, mortality rates remain high, and adherence to sepsis bundle components in Korea is low. To address this, the Korean Sepsis Alliance, affiliated with the Korean Society of Critical Care Medicine, developed the first sepsis treatment guidelines for Korea based on a comprehensive systematic review and meta-analysis. Methods A de novo method was used to develop the guidelines. Methodologies included determining key questions, conducting a literature search and selection, assessing the risk of bias, synthesizing evidence, and developing recommendations. The certainty of evidence and the strength of recommendations were determined using the Grading of Recommendations, Assessment, Development, and Evaluations approach. Draft recommendations underwent internal and external review processes and public hearings. The development of these guidelines was supported by a research grant from the Korean Disease Control and Prevention Agency. Results In these guidelines, we focused on early treatments for adult patients with sepsis and septic shock. Through the guideline development process, 12 key questions and their respective recommendations were formulated. These include lactate measurement, fluid therapies, target blood pressure, antibiotic administration, use of vasopressors and dobutamine, extracorporeal membrane oxygenation, and echocardiography. Conclusions These guidelines aim to support medical professionals in making appropriate decisions about treating adult sepsis and septic shock. We hope these guidelines will increase awareness of sepsis and reduce its mortality rate.http://www.accjournal.org/upload/pdf/acc-2024-00920.pdfguidelinesoutcomesepsisseptic shocktreatment |
| spellingShingle | Chul Park Nam Su Ku Dae Won Park Joo Hyun Park Tae Sun Ha Do Wan Kim So Young Park Youjin Chang Kwang Wook Jo Moon Seong Baek Yijun Seo Tae Gun Shin Gina Yu Jongmin Lee Yong Jun Choi Ji Young Jang Yun Tae Jung Inseok Jeong Hwa Jin Cho Ala Woo Sua Kim Dae-Hwan Bae Sung Wook Kang Sun Hyo Park Gee Young Suh Sunghoon Park Early management of adult sepsis and septic shock: Korean clinical practice guidelines Acute and Critical Care guidelines outcome sepsis septic shock treatment |
| title | Early management of adult sepsis and septic shock: Korean clinical practice guidelines |
| title_full | Early management of adult sepsis and septic shock: Korean clinical practice guidelines |
| title_fullStr | Early management of adult sepsis and septic shock: Korean clinical practice guidelines |
| title_full_unstemmed | Early management of adult sepsis and septic shock: Korean clinical practice guidelines |
| title_short | Early management of adult sepsis and septic shock: Korean clinical practice guidelines |
| title_sort | early management of adult sepsis and septic shock korean clinical practice guidelines |
| topic | guidelines outcome sepsis septic shock treatment |
| url | http://www.accjournal.org/upload/pdf/acc-2024-00920.pdf |
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