Potential differences in receptor‐mediated G‐protein activation in postmortem human hippocampal membranes prepared from healthy controls and suicide victims

Potential differences in receptor‐mediated G‐protein activation in postmortem human hippocampal membranes prepared from healthy controls and suicide victims

Abstract Aim Postmortem brain studies offer enormous opportunities to study molecular mechanisms associated with suicide. In the present study, conventional [35S]GTPγS binding assay and its version‐up method ([35S]GTPγS binding/immunoprecipitation assay) were applied to postmortem human hippocampal...

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Bibliographic Details
Main Authors: Yuji Odagaki, Masakazu Kinoshita, Miklós Palkovits, Dasiel Oscar Borroto‐Escuela, Kjell Fuxe
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Neuropsychopharmacology Reports
Subjects:
[35S]GTPγS binding
G‐protein
human hippocampus
postmortem brain study
suicide
Online Access:https://doi.org/10.1002/npr2.12484
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