Case report: administration of immune checkpoint inhibitor for SMARCB1 (INI1)-negative rhabdoid carcinoma with microsatellite instability (MSI)-high in the right colon

Case report: administration of immune checkpoint inhibitor for SMARCB1 (INI1)-negative rhabdoid carcinoma with microsatellite instability (MSI)-high in the right colon

Abstract Background Malignant tumors with rhabdoid features are rare, highly aggressive, and some of them are characterized by SMARCB1 (INI1) loss. Although cases of rhabdoid carcinoma are extremely rare, its occurrence in the colon has been reported previously. Case presentation A 71-year-old Japan...

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Bibliographic Details
Main Authors: Toshinori Kobayashi, Yuki Matsui, Hisanori Miki, Masahiko Hatta, Mitsuaki Ishida, Hironaga Satake, Mitsugu Sekimoto
Format: Article
Language:English
Published: Japan Surgical Society 2023-02-01
Series:Surgical Case Reports
Subjects:
SMARCB1
INI1
Rhabdoid carcinoma
MSI-high
Pembrolizumab
Immune checkpoint inhibitors
Online Access:https://doi.org/10.1186/s40792-023-01594-y
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