Excess Ub-K48 Induces Neuronal Apoptosis in Alzheimer’s Disease

Excess Ub-K48 Induces Neuronal Apoptosis in Alzheimer’s Disease

Background: K48-linked ubiquitin chain (Ub-K48) is a crucial ubiquitin chain implicated in protein degradation within the ubiquitin-proteasome system. However, the precise function and molecular mechanism underlying the role of Ub-K48 in the pathogenesis of Alzheimer’s disease (AD...

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Bibliographic Details
Main Authors:	Qiang Li, Yiyuan Yuan, Shi Huang, Guangfu Di, Haoyuan Chen, Yani Zhuang, Wanzhen Fang, Yanjiao Huang, Yinan Tao, Jing Jiang, Zhiliang Xu
Format:	Article
Language:	English
Published:	IMR Press 2024-12-01
Series:	Journal of Integrative Neuroscience
Subjects:	alzheimer’s disease ub-k48 p-tau apoptosis
Online Access:	https://www.imrpress.com/journal/JIN/23/12/10.31083/j.jin2312223
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