Human Epidermal Growth Factor Receptor 2 [HER‐2/neu] Amplification and Microsatellite Stable Status in Gastric and Gastroesophageal Adenocarcinoma: Assessing Frequency and Prognostic Implications at the Cancer Institute of Iran

ABSTRACT Background Molecular targeted therapy and immunotherapy have shown promise in managing gastric adenocarcinoma. The amplified expression of Human epidermal growth factor receptor‐2 (HER‐2) and microsatellite stable (MSI) status serve as indicators of response to targeted therapy and immunoth...

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Main Authors: Samaneh Salarvand, Abbas Mohammadi, Reza Shahsiah, Farzaneh Bagheri, Mahsa Gholizadeh, Somayeh Jolany‐Vangah, Ebrahim Esmati, Marzieh Lashkari, Vahid Soleymani, Seraj Zareh‐Dehabadi, Vahid Mehrtash, Amirmohsen Jalaeefar, Mohammad Shirkhoda, Moones Toosang, Romina Abyaneh, Reza Ghalehtaki
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Reports
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Online Access:https://doi.org/10.1002/cnr2.70314
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