Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy

Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy

Background: Osteosarcoma (OS) is a common primary malignant tumor of bone, most commonly seen in children and adolescents, which has a low survival rate and is a serious threat to patients' lives. Honokiol (HKL) is the main active components of Magnolia officinalis, which have significant anti-...

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Bibliographic Details
Main Authors: Jian Wu, Wenqiang Xu, Jingchi Li, Cheng Luo, Bo Chen, Luo Lin, Tianyu Huang, Tao Luo, Lin Yang, Jiexiang Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular and Cellular Probes
Subjects:
Honokiol
MG63 cell
Osteosarcoma
FTO
Smad6
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0890850824000409
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