Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population
Objectives Individuals with obesity especially excessive visceral adiposity have high risk for incident hypertension. Recently, a new algorithm named relative fat mass (RFM) was introduced to define obesity. Our aim was to investigate whether it can predict hypertension in Chinese population and to...
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BMJ Publishing Group
2020-10-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/10/e038420.full |
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| author | Xuefeng Yu Peng Yu Teng Huang Senlin Hu |
| author_facet | Xuefeng Yu Peng Yu Teng Huang Senlin Hu |
| author_sort | Xuefeng Yu |
| collection | DOAJ |
| description | Objectives Individuals with obesity especially excessive visceral adiposity have high risk for incident hypertension. Recently, a new algorithm named relative fat mass (RFM) was introduced to define obesity. Our aim was to investigate whether it can predict hypertension in Chinese population and to compare its predictive power with traditional indices including body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR).Design A 6-year prospective study.Setting Nine provinces (Hei Long Jiang, Liao Ning, Jiang Su, Shan Dong, He Nan, Hu Bei, Hu Nan, Guang Xi and Gui Zhou) in China.Participants Those without hypertension in 2009 survey and respond in 2015 survey.Intervention Logistic regression were performed to investigate the association between RFM and incident hypertension. Receiver operating characteristic (ROC) analysis was performed to compare the predictive ability of these indices and define their optimal cut-off values.Main outcome measures Incident hypertension in 2015.Results The prevalence of incident hypertension in 2015 based on RFM quartiles were 14.8%, 21.2%, 26.8% and 35.2%, respectively (p for trend <0.001). In overall population, the OR for the highest quartile compared with the lowest quartile for RFM was 2.032 (1.567–2.634) in the fully adjusted model. In ROC analysis, RFM and WHtR had the highest area under the curve (AUC) value in both sexes but did not show statistical significance when compared with AUC value of BMI and WC in men and AUC value of WC in women. The performance of the prediction model based on RFM was comparable to that of BMI, WC or WHtR.Conclusions RFM can be a powerful indictor for predicting incident hypertension in Chinese population, but it does not show superiority over BMI, WC and WHtR in predictive power. |
| format | Article |
| id | doaj-art-17be9b7ced1d48c881b8e00fc509d7bb |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2020-10-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open |
| spelling | doaj-art-17be9b7ced1d48c881b8e00fc509d7bb2024-11-16T06:25:11ZengBMJ Publishing GroupBMJ Open2044-60552020-10-01101010.1136/bmjopen-2020-038420Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese populationXuefeng Yu0Peng Yu1Teng Huang2Senlin Hu3Department of Internal Medicine, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Cardiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China1 University of Macau, Taipa, Macau, ChinaDepartment of Internal Medicine, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, ChinaObjectives Individuals with obesity especially excessive visceral adiposity have high risk for incident hypertension. Recently, a new algorithm named relative fat mass (RFM) was introduced to define obesity. Our aim was to investigate whether it can predict hypertension in Chinese population and to compare its predictive power with traditional indices including body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR).Design A 6-year prospective study.Setting Nine provinces (Hei Long Jiang, Liao Ning, Jiang Su, Shan Dong, He Nan, Hu Bei, Hu Nan, Guang Xi and Gui Zhou) in China.Participants Those without hypertension in 2009 survey and respond in 2015 survey.Intervention Logistic regression were performed to investigate the association between RFM and incident hypertension. Receiver operating characteristic (ROC) analysis was performed to compare the predictive ability of these indices and define their optimal cut-off values.Main outcome measures Incident hypertension in 2015.Results The prevalence of incident hypertension in 2015 based on RFM quartiles were 14.8%, 21.2%, 26.8% and 35.2%, respectively (p for trend <0.001). In overall population, the OR for the highest quartile compared with the lowest quartile for RFM was 2.032 (1.567–2.634) in the fully adjusted model. In ROC analysis, RFM and WHtR had the highest area under the curve (AUC) value in both sexes but did not show statistical significance when compared with AUC value of BMI and WC in men and AUC value of WC in women. The performance of the prediction model based on RFM was comparable to that of BMI, WC or WHtR.Conclusions RFM can be a powerful indictor for predicting incident hypertension in Chinese population, but it does not show superiority over BMI, WC and WHtR in predictive power.https://bmjopen.bmj.com/content/10/10/e038420.full |
| spellingShingle | Xuefeng Yu Peng Yu Teng Huang Senlin Hu Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population BMJ Open |
| title | Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population |
| title_full | Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population |
| title_fullStr | Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population |
| title_full_unstemmed | Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population |
| title_short | Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population |
| title_sort | predictive value of relative fat mass algorithm for incident hypertension a 6 year prospective study in chinese population |
| url | https://bmjopen.bmj.com/content/10/10/e038420.full |
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