Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension
OBJECTIVE: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients. METHODS: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated. RESULTS: There was no significant...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2012-02-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000200008&lng=en&tlng=en |
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| _version_ | 1849308779060920320 |
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| author | Arthur Oscar Schelp Cristiane Lara Mendes-Chiloff Rodrigo Bazan Vanessa Cristina Paduan Ana Beatriz Maringolo Pioltini |
| author_facet | Arthur Oscar Schelp Cristiane Lara Mendes-Chiloff Rodrigo Bazan Vanessa Cristina Paduan Ana Beatriz Maringolo Pioltini |
| author_sort | Arthur Oscar Schelp |
| collection | DOAJ |
| description | OBJECTIVE: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients. METHODS: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated. RESULTS: There was no significant effect from the presence of hypertension (OR=2.36 for patients under 65 years old and OR=0.64 for patients over 65), diabetes or hypercholesterolemia regarding occurrences of dementia associated with PD (24% of the patients). The study demonstrated that each year of age increased the estimated risk of dementia in PD patients by 9% (OR=1.09; 95%CI: 1.01-1.17). CONCLUSION: There was no evidence to correlate the presence of metabolic syndrome with the risk of dementia that was associated with PD. The study confirmed that dementia in PD is age dependent and not related to disease duration. |
| format | Article |
| id | doaj-art-17841c9f827f4e5fa5d1cee88b80a25d |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2012-02-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-17841c9f827f4e5fa5d1cee88b80a25d2025-08-20T03:54:20ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272012-02-0170211411810.1590/S0004-282X2012000200008S0004-282X2012000200008Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertensionArthur Oscar Schelp0Cristiane Lara Mendes-Chiloff1Rodrigo Bazan2Vanessa Cristina Paduan3Ana Beatriz Maringolo Pioltini4Universidade Estadual PaulistaUniversidade Estadual PaulistaUniversidade Estadual PaulistaUniversidade Estadual PaulistaUniversidade Estadual PaulistaOBJECTIVE: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients. METHODS: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated. RESULTS: There was no significant effect from the presence of hypertension (OR=2.36 for patients under 65 years old and OR=0.64 for patients over 65), diabetes or hypercholesterolemia regarding occurrences of dementia associated with PD (24% of the patients). The study demonstrated that each year of age increased the estimated risk of dementia in PD patients by 9% (OR=1.09; 95%CI: 1.01-1.17). CONCLUSION: There was no evidence to correlate the presence of metabolic syndrome with the risk of dementia that was associated with PD. The study confirmed that dementia in PD is age dependent and not related to disease duration.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000200008&lng=en&tlng=endemênciadoença de Parkinsondislipidemiahipertensão |
| spellingShingle | Arthur Oscar Schelp Cristiane Lara Mendes-Chiloff Rodrigo Bazan Vanessa Cristina Paduan Ana Beatriz Maringolo Pioltini Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension Arquivos de Neuro-Psiquiatria demência doença de Parkinson dislipidemia hipertensão |
| title | Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension |
| title_full | Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension |
| title_fullStr | Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension |
| title_full_unstemmed | Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension |
| title_short | Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension |
| title_sort | metabolic syndrome and dementia associated with parkinson s disease impact of age and hypertension |
| topic | demência doença de Parkinson dislipidemia hipertensão |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000200008&lng=en&tlng=en |
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