Spatial heterogeneity of the hepatocellular carcinoma microenvironment determines the efficacy of immunotherapy
Abstract Hepatocellular carcinoma (HCC) remains a global health challenge owing to its widespread incidence and high mortality. HCC has a specific immune tolerance function because of its unique physiological structure, which limits the efficacy of chemotherapy, radiotherapy, and molecular targeting...
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Main Authors: | Minni Zhang, Kailin Huang, Qiushi Yin, Xueqin Wu, Mingyue Zhu, Mengsen Li |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Discover Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s12672-025-01747-5 |
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