Use of cerebral hemorrhage volume calculation methods in patients with ASPECTS <6

Objective: We aimed to determine whether the ABC/2 can be used as an infarct volume measurement tool for Mechanical thrombectomy (MT) in patients with Alberta Stroke Program Early CT Scores (ASPECTS) < 6. Methods: Patients with stroke with ASPECTS <6 within 24 h were included in this study, an...

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Bibliographic Details
Main Authors: Jia Zhou, Chenyang Huang, Hai Zeng
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024164523
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Summary:Objective: We aimed to determine whether the ABC/2 can be used as an infarct volume measurement tool for Mechanical thrombectomy (MT) in patients with Alberta Stroke Program Early CT Scores (ASPECTS) < 6. Methods: Patients with stroke with ASPECTS <6 within 24 h were included in this study, and infarct volume was measured using the ABC/2. The patients were categorized into MT and standard drug groups. They were assessed based on a modified Rankin Scale (mRS) ≤3 at 3 months, intracranial hemorrhage within 48 h, and mortality at 3 months. Results: ASPECTS <6 showed a significant negative correlation with infarct volume measured using the ABC/2. Compared to drug therapy, the patients who received MT treatment had a higher proportion of achieving an mRS score of ≤3 (OR, 2.60; 95 % confidence interval [CI], 1.04–6.50; P = 0.040), a lower death rate (OR, 0.37; 95 % CI, 0.15–0.92; P = 0.031), and a reduced decompressive craniectomy (OR, 0.10; 95 % CI, 0.01–0.83; P = 0.033); however, intracranial hemorrhage risk significantly increased (OR, 4.35; 95 % CI, 1.12–17.0; P = 0.034). Conclusion: In the absence of advanced imaging, the ABC/2 can be a useful tool for measuring volume in anterior circulation in patients with ASPECTS <6.
ISSN:2405-8440