Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy

Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy

BackgroundEsophageal cancer has a poor prognosis despite treatment advancements. Although the benefit of neoadjuvant chemoradiotherapy (CRT) followed by adjuvant immunotherapy is evident, the effects of CRT on PD-L1 expression in esophageal cancer are not well understood. This study examines the imp...

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Bibliographic Details
Main Authors: Lovis Hampe, Stefan Küffer, Tim Niemeier, Niklas Christian Scheele, Laetitia Zoe Hampe, Anna Luisa Riedl, Laura Anna Fischer, David Alexander Ziegler, Martin Leu, Leif Hendrik Dröge, Alexander König, Michael Ghadimi, Friederike Braulke, Stefan Rieken, Hanibal Bohnenberger, Rami A. El Shafie
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
esophageal cancer
immunotherapy
programmed-death-ligand-1
checkmate-577
CROSS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1509051/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1509051/full

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