Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cells

Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cells

Abstract Oxidised low-density lipoprotein cholesterol (ox-LDL) is critical in the initiation and progression of atherosclerosis. While excessive atherogenic lipids in the arterial intima can trigger endothelial dysfunction in advanced lesions, the response of endothelial cells to ox-LDL in the early...

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Main Authors: Jiahao Jiang, Thomas K. Hiron, Anil Chalisey, Yashaswat Malhotra, Thomas Agbaedeng, Chris A. O’Callaghan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-07763-3
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